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REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts

NCT04667078 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 368

Last updated 2026-03-02

No results posted yet for this study

Summary

The main objective is to evaluate the efficacy of IV administration of the P2Y12 inhibitor (cangrelor) in addition to mecanich thrombectomy and WMD versus mecanich thrombectomy and WMD alone on the functional prognosis at 3 months, in patients with acute ischemic stroke eligible for mecanich thrombectomy on the basis of infusion imaging between 0 and 24 hours after the onset of symptoms.

Conditions

  • Acute Ischemia

Interventions

DRUG

Cangrelor

administration of cangrolor by iv befor thrombectomy

OTHER

best medical management

used yhe best medical management

Sponsors & Collaborators

  • Ministry of Health, France

    collaborator OTHER_GOV

  • Fondation Ophtalmologique Adolphe de Rothschild

    lead NETWORK

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-02
Primary Completion
2030-03-01
Completion
2030-09-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04667078 on ClinicalTrials.gov