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Function Integrity of Neck Anatomy in Thyroid Surgery

NCT04666103 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1264

Last updated 2020-12-14

No results posted yet for this study

Summary

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.

Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Conditions

  • Thyroid Carcinoma
  • Thyroid Nodule (Benign)
  • Ablation; Retina

Interventions

PROCEDURE

Intraoperative thermal ablation

After the thyroid lobectomy, the contralateral benign thyroid nodule was treated with intraoperative thermal ablation. The "hydrodissection technique'' was used during the ablation process to prevent recurrent laryngeal nerve, esophageal and other important structures from being destroyed by heat energy.

Sponsors & Collaborators

  • Wuhan University

    lead OTHER

Principal Investigators

  • Gaosong Wu, Ph.D. · Department of Breast and Thyroid Surgery, Zhongnan Hospital of Wuhan University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-11
Primary Completion
2021-12-31
Completion
2026-12-12

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04666103 on ClinicalTrials.gov