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Effect of Carotid Artery Stent on Evoked Cerebral Blood Oxygenation and Neurocognitive Functioning

NCT04651998 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2024-05-29

No results posted yet for this study

Summary

Cerebral hemodynamic compromise from internal carotid artery stenosis may be a cause of vascular cognitive impairment that is amenable to treatment by revascularization. The effect of carotid artery stent on evoked cerebral blood oxygenation and neurocognitive functioning will be evaluated by functional near-infrared spectroscopy. Carotid artery stent could benefit cerebral blood oxygenation after stent and improving neurocognitive functioning after 6 months.

Conditions

  • Carotid Artery Stenosis

Interventions

DIAGNOSTIC_TEST

MMSE, MoCA, functional near-infrared spectroscopy

MMSE and MoCA are used for cognitive test before carotid artery stent implant and 6 months later. Cerebral blood oxygenation is evaluated by functional near-infrared spectroscopy under the mental task before and after revascularization within one week, 6 months later respectively.

Sponsors & Collaborators

  • Minhang Hospital, Fudan University

    collaborator UNKNOWN

  • Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

    collaborator OTHER

  • RenJi Hospital

    collaborator OTHER

  • ShuGuang Hospital

    collaborator OTHER

  • Shanghai Jiao Tong University Affiliated Sixth People's Hospital

    lead OTHER

Principal Investigators

  • Yueqi Zhu, PhD · Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Eligibility

Min Age
35 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2024-09-30
Completion
2024-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04651998 on ClinicalTrials.gov