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Dose of Magnesium Sulfate Infusion in Obese

NCT04645719 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2023-10-31

No results posted yet for this study

Summary

Magnesium sulfate has been shown to be a successful tool in a large number of clinical areas. Its benefits include neuroprotection, control of eclampsia / pre-eclampsia, control of intraoperative blood pressure, decreased neuroendocrine response during laryngoscopy and tracheal intubation and reduced levels of postoperative pain and consumption of analgesic.

Obese patients have become more and more frequent in the operating rooms, due to the increasing prevalence of this population worldwide. However, although they have received magnesium sulfate as part of the analgesic strategy in many centers, there has been no study demonstrating the appropriate dose of this medication in obese patients.

This study aims to compare two doses of magnesium sulfate in obese patients: based on their real weight or based on ideal weight.

Conditions

Interventions

OTHER

Lactate ringer group

General anesthesia only

DRUG

Magnesium sulfate dose through real weight group

General anesthesia + magnesium sulfate 15 mg.kg-1.h-1 based on the patient's real weight

DRUG

Magnesium sulfate dose through corrected ideal weight group

General anesthesia + magnesium sulfate 15 mg.kg-1.h-1 based on the patient's corrected ideal weight

Sponsors & Collaborators

  • University of Sao Paulo General Hospital

    lead OTHER

Principal Investigators

  • sebastião silva filho · Hospital da Sociedade de Beneficência Portuguesa d

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2025-06-01
Completion
2025-12-01

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04645719 on ClinicalTrials.gov