A Study Evaluates the Safety and Efficacy of WX-0593 in ALK -Positive, or ROS1-positive Non-small Cell Lung Cancer
NCT04641754 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 176
Last updated 2020-11-24
Summary
The purpose of the study is to evaluate safety and efficacy of WX-0593 oral tablets in ALK -positive, or ROS1-positive non-small cell lung cancer (NSCLC)
Conditions
Interventions
- DRUG
-
WX-0593 Tablets
tablets, 60 mg→180mg, quaque die（QD）
Sponsors & Collaborators
-
Qilu Pharmaceutical Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-07
- Primary Completion
- 2020-12-31
- Completion
- 2021-03-31
Countries
- China
Study Locations
More Related Trials
-
Assessing the Safety and Efficacy of PLB1004 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
NCT05347628 ·Status: UNKNOWN ·Phase: PHASE1
-
Biweekly Schedule of Docetaxel and Cisplatin in High Risk Patients With Unresectable Non-small Cell Lung Cancer (NSCLC)
NCT00995761 ·Status: COMPLETED ·Phase: PHASE2
-
KN046 in Subjects With Advanced Squamous Non-small Cell Lung Cancer
NCT04474119 ·Status: UNKNOWN ·Phase: PHASE3
-
Neoadjuvant Immunotherapy With Chemotherapy for Stage I-IIIB Non-Small Cell Lung Cancer Patients
NCT04941417 ·Status: UNKNOWN ·Phase: PHASE2
-
A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung
NCT01154140 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel Detection in NSCLC Treated With TC Regimen
NCT02737709 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease
NCT01702714 ·Status: WITHDRAWN ·Phase: PHASE1
-
Clinical Study of Neoadjuvant Chemotherapy and Immunotherapy Combined With Probiotics in Patients With Resectable NSCLC
NCT04699721 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of QL1706 Combined With Platinum-containing Chemotherapy in Adjuvant Treatment of Stage II-IIIB Non-small Cell Lung Cancer After Complete Surgical Resection.
NCT05487391 ·Status: RECRUITING ·Phase: PHASE3
-
A Phase II Study of Rulonilimab Combined With Chemotherapy in the First-Line Treatment for Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
NCT05741021 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy Study of rhAngiostatin Administered in Combination With Paclitaxel and Carboplatin to Patients With Non-Small-Cell Lung Cancer
NCT00049790 ·Status: COMPLETED ·Phase: PHASE2
-
Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI
NCT06343064 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Anti-PD-1 AK105 in Patients With Metastatic Squamous Non-small Cell Lung Cancer
NCT03866993 ·Status: COMPLETED ·Phase: PHASE3
-
Individualized Chemotherapy Based on BRCA1 and RRM1 mRNA for Advanced Non-small Cell Lung Cancer (NSCLC)
NCT01424709 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy of Xalkori ROS1
NCT03375242 ·Status: ACTIVE_NOT_RECRUITING
-
A Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous Histology
NCT02204345 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung
NCT01561456 ·Status: COMPLETED ·Phase: PHASE2
-
PD-L1/PD-1 Inhibitors Plus Chemotherapy Versus Chemotherapy Alone for the Neoadjuvant Treatment of Limited-stage SCLC
NCT06375109 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
First-Line Treatment for Advanced Non-squamous Non-Small-Cell Lung Cancer With Negative Driver Gene: a Single-center, Single-Arm Trial
NCT05648071 ·Status: UNKNOWN ·Phase: PHASE3
-
PD-L1 Inhibitor Rechallenge After PD-1 Immunotherapy for Patients With Solid Tumor Beyond Lung Cancer
NCT05325684 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)
NCT00991796 ·Status: COMPLETED ·Phase: PHASE2
-
Anlotinib in Treatment of Recurrent Small Cell Lung Cancer
NCT03732846 ·Status: UNKNOWN ·Phase: PHASE2
-
A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
NCT05943795 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of Irinotecan Liposome Injection as Second-line Regimen in Patients With Small Cell Lung Cancer (SCLC)
NCT04727853 ·Status: COMPLETED ·Phase: PHASE2
-
AK104 With Chemotherapy as Neoadjuvant and Adjuvant Therapy for Resectable Non-small Cell Lung Cancer
NCT05377658 ·Status: RECRUITING ·Phase: PHASE2