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Lidocaine on Early Cognitive Dysfunction in Shoulder Arthroscopy

NCT04634656 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2021-01-08

No results posted yet for this study

Summary

The beach chair position (BCP) combined with deliberate hypotension impair cerebral perfusion pressure and oxygenation during arthroscopic shoulder surgeries and produce cerebral ischemia.

Conditions

  • Cognitive Dysfunction, Postoperative

Interventions

DRUG

Lidocaine

Patients will receive lidocaine in a loading dose of 1 mg/ kg diluted in 10 ml of normal saline that will be infused over 5 minutes after induction of anesthesia then followed by a continuous infusion at 1.5 mg/ kg/ h diluted in normal saline to a volume of 50 ml until the end of surgery

DRUG

Normal saline

Patients will receive normal saline after induction of anesthesia with the same volume and rate changes as lidocaine group until the end of surgery

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Seham M Moeen, MD · Assiut University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-07
Primary Completion
2021-11-10
Completion
2021-11-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04634656 on ClinicalTrials.gov