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Nasal Septum Perforation Treatment Using Tissue Engineered Cartilage Graft

NCT04633928 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2023-05-03

No results posted yet for this study

Summary

The purpose of this study is to investigate the safety and feasibility of implanting an engineered cartilage tissue in an interposition graft with a temporoparietal fascia (TPF) flap to repair medium size septal perforation. The engineered cartilage graft is obtained by culturing expanded autologous nasal chondrocytes within a collagen type I/III membrane. In addition, first data on efficacy will be collected.

Conditions

  • Nasal Cartilage Septum Perforations

Interventions

BIOLOGICAL

N-TEC: Autologous nasal chondrocytes and ECM proteins

Cells expanded in vitro and cultured in a collagen type I//III scaffold

Sponsors & Collaborators

  • Dr Josef Vavrina, HNO Seepraxen, CH-8810 Horgen, Zurich

    collaborator UNKNOWN

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Martin Haug, Prof · University Hospital Basel, Basel, Switzerland

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-09
Primary Completion
2023-04-24
Completion
2023-04-24

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04633928 on ClinicalTrials.gov