Preadmission Metformin Exposure and Incidence of Acute Kidney Injury
NCT04631289 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3841
Last updated 2020-11-17
Summary
More than 50% of ICU patients suffer from Acute kidney injury (AKI). Metformin shows protective properties in kidney disease. Our study aimed to validate AKI incidence among diabetes patients in the ICU with or without preadmission metformin exposure. We included non-AKI patients with type 2 diabetes in Medical Information Mart for Intensive Care (MIMIC)-III database. Incidence of AKI and mortality were compared between those with and without preadmission prescriptions.
Conditions
Sponsors & Collaborators
-
Second Affiliated Hospital of Guangzhou Medical University
lead OTHER
Principal Investigators
-
Shikun Qian · Second Affiliated Hospital of Guangzhou Medical University
Eligibility
- Min Age
- 16 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-08-01
- Primary Completion
- 2020-09-01
- Completion
- 2020-11-10
Countries
- China
Study Locations
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