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Prognostic Implication of Angiography-Derived IMR in STEMI Patients

NCT04628377 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 333

Last updated 2023-04-12

No results posted yet for this study

Summary

Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of STEMI patients. Previous study presented that index of microcirculatory resistance (IMR) in culprit vessel of STEMI patients showed significant association with the risk of cardiac death or heart failure admission. Recent technical development enabled angiographic derivation of IMR without pressure wire, hyperemic agents, or theromdilution method. In this regard, the current study will evaluate prognostic implication of angiography-derived IMR in STEMI patients who were successfully revascularized.

Conditions

  • Acute ST-segment Elevation Myocardial Infarction

Interventions

DEVICE

Angiography-drived Index of Microcirculatory Resistance

From coronary angiographic images, angiography-derived IMR will be calculated based on mathematical calculation. Angiography-derived IMR = (hyperemic Pa x angiography-derived FFR) x (vessel length / {K x V diastole}). Hyperemic Pa will be estimated from resting Pa according to prespecified equation.

Sponsors & Collaborators

  • RainMed Medical Group

    collaborator INDUSTRY

  • Samsung Medical Center

    lead OTHER

Principal Investigators

  • Joo Myung Lee, MD, MPH, PhD · Samsung Medical Center

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-05-26
Primary Completion
2023-03-01
Completion
2023-04-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04628377 on ClinicalTrials.gov