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ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients

NCT04626960 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2020-11-13

No results posted yet for this study

Summary

Aims: To evaluate changes in levels of ADRB3, ROCK2, and GEF which have key roles in the adrenergic and cholinergic pathways of contraction-relaxation harmony in voiding physiology, and to investigate the diagnostic potential of these proteins in OAB.

Methods: This study included 60 idiopathic OAB patients and a healthy control group. All patients completed a validated OAB-V8 questionnaire. Serum levels of ADRB3, ROCK2, and GEF were examined by ELISA. ROC curves were generated to evaluate the diagnostic performance of these protein levels for OAB diagnosis.

Conditions

Sponsors & Collaborators

  • Pamukkale University

    lead OTHER

Principal Investigators

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-05
Primary Completion
2019-12-12
Completion
2020-06-07

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04626960 on ClinicalTrials.gov