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Non-invasive Assessment of Colonic Motility

NCT04624334 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2022-05-19

No results posted yet for this study

Summary

The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures. To improve this diagnostic process, the potential of Electro-Entero-Graphy (EEnG) is investigated.

During the EEnG procedure, several surface electrodes are positioned (under ultrasound guidance) on the abdomen so that electrical activity originating in the colon can be measured. Measurements will be performed after a period of fasting (when the colon is 'silent') and just after a meal (when the colon is moving) in both participants suffering from colonic motility disorders and healthy controls.

It is hypothesized that these measurements are an indication of colonic motility and can be used as a diagnostic tool for colonic motility disorders. It is also hypothesized that this EEnG procedure is not more burdensome than the Gold Standard procedures for diagnosing colonic motility disorders. This will be assessed using questionnaires.

Conditions

  • Colon Disease
  • Functional Constipation
  • Electroenterography
  • Slow Transit
  • Hirschsprung Disease

Interventions

OTHER

Elektro-Entero-Graphy procedure

Fasting, after which pre- and postprandial EEnG measurements are performed.

OTHER

EEnG Questionnaire

Filling out questionnaire about EEnG procedure.

OTHER

Gold Standard Questionnaire

Filling out questionnaire about Gold Standard diagnostic used to diagnose colonic motility disorder.

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • S.M.B.I. Botden, MD · Radboud University Medical Center

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-02-25
Primary Completion
2022-05-12
Completion
2022-05-12

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04624334 on ClinicalTrials.gov