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Impact of Operation on Fertility for Women With Severe Endometriosis

NCT04610710 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 38

Last updated 2026-03-10

No results posted yet for this study

Summary

The EFFORT study compares the impact on fertility of operation or fertility treatment (IVF, in vitro fertilization) in a multicenter randomized controlled trial. The study population consists of women with colorectal deep infiltrating endometriosis and a pregnancy intention. These women will be randomized to either of the two treatment groups: Group A = Operation or Group B = fertility treatment (IVF). Group A will be further divided postoperatively into spontaneous conception or IVF depending on the Endometriosis Fertility Index score.

Conditions

  • Deep Endometriosis
  • Infertility, Female

Interventions

PROCEDURE

Operation

Operation for deep infiltrating endometriosis

PROCEDURE

Fertility treatment

In vitro fertilisation (IVF) and IVF-intracytoplasmic injection (ICSI)

Sponsors & Collaborators

  • Aarhus University Hospital

    collaborator OTHER

  • Clinique Tivoli Ducos

    collaborator OTHER

  • Horsens Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
38 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-25
Primary Completion
2026-03-01
Completion
2026-03-01

Countries

  • Denmark
  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04610710 on ClinicalTrials.gov