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Comparison of Potassium Binders in the ER

NCT04585542 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 37

Last updated 2026-04-22

Study results available
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Summary

Compare efficacy of 3 oral potassium binders (cation exchange resins) on lowering blood potassium, in hospital patients with acute hyperkalemia.

Conditions

  • Acute Hyperkalemia
  • Oral Potassium Binders

Interventions

DRUG

Polyethylene Glycol 3350

Nonspecific laxative comparison group.

DRUG

Sodium Polystyrene Sulfonate Oral Suspension [SPS]

Potassium binder to treat hyperkalemia.

DRUG

Patiromer

Potassium binder to treat hyperkalemia.

DRUG

Sodium zirconium cyclosilicate

Potassium binder to treat hyperkalemia.

Sponsors & Collaborators

  • University of California, Irvine

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-20
Primary Completion
2025-01-31
Completion
2025-01-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04585542 on ClinicalTrials.gov