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Lidocaine And Neuromonitoring in Thyroid Surgery

NCT04574947 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2024-03-21

No results posted yet for this study

Summary

The aim of this study is to test the hypothesis that the quality of recovery with topical lidocaine is better than placebo.

Conditions

  • Thyroid Neoplasm
  • Parathyroid Neoplasms
  • Anesthesia

Interventions

DRUG

Intravenous lidocaine

Lidocaine IV 1.5 mg / kg BMI will be administered during induction into anaesthesia followed by infusion at a dose of 1.5 mg / kg / h until the end of the surgery.

DRUG

Intravenous placebo

During induction and maintenance of anaesthesia, 0.9% sodium chloride solution will be injected intravenously at a rate equivalent to lidocaine solution.

PROCEDURE

Intra-cuff lidocaine

The lidocaine solution will be applied to the intubation tube and the cuff will be filled with an alkalinised lidocaine solution.

PROCEDURE

Intra-cuff placebo

The intubation tube will be lubricated 0.9% sodium chloride, the tube cuff will be filled with 0.9% sodium chloride solution.

Sponsors & Collaborators

  • Saint Petersburg State University, Russia

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-25
Primary Completion
2023-10-15
Completion
2023-12-31

Countries

  • Russia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04574947 on ClinicalTrials.gov