Diagnostic Performance of Plasma Procalcitonin for the Detection of Blood Cultures Contaminations
NCT04573894 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 147
Last updated 2020-10-05
Summary
In blood cultures, species considered as potentially contaminating (coagulase negative staphylococci (CNS), Bacillus spp., Corynebacterium spp., Cutibacterium acnes, Micrococcus spp., viridans group streptococci, and Clostridium perfringens) can, however, be responsable for true bacteremia.
Blood levels of the prohormone procalcitonin (PCT) markedly increase in the early stages of bacterial infections. The aim of our study is to determine the role of plasma PCT as a biomarker differentiating blood culture contaminations from true bacteremia.
Conditions
- Blood Culture Contamination
- Bacteremia
- Contamination
Interventions
- DIAGNOSTIC_TEST
-
Procalcitonin dosage
Plasma PCT levels measured by automated enzyme immunoassay (Kryptor).
Sponsors & Collaborators
-
Central Hospital, Nancy, France
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-01
- Primary Completion
- 2020-07-31
- Completion
- 2020-09-05
Countries
- France
Study Locations
More Related Trials
-
Virulence of Staphylococcus Lugdunensis in Severe Infections
NCT02026895 ·Status: COMPLETED ·Phase: NA
-
Resistell Phenotech AST to Determine the Antibiotic Susceptibility of Gram-negative Bacteria Causing Bacteremia
NCT05613322 ·Status: TERMINATED
-
Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients with Enterobacterales Bacteremia
NCT06425367 ·Status: RECRUITING ·Phase: NA
-
Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection
NCT02482961 ·Status: COMPLETED
-
Clinical Impact of Rapid AST Directly From Blood Cultures
NCT03992703 ·Status: COMPLETED
-
The Only Blood Culture for Diagnosis of Bacteremia - Comparative Study of Practice
NCT02516514 ·Status: COMPLETED ·Phase: NA
-
Rapid Detection of Bacterial Resistance by MALDI-TOF MS and Antibiotic Savings
NCT02860247 ·Status: COMPLETED
-
Pharmacological Study of High Doses of Ceftriaxone in Meningitidis
NCT01745679 ·Status: COMPLETED ·Phase: PHASE4
-
PCR Technic Evaluation in the Microbial Diagnostic of Septicemia in Hemodialysis Patients With Catheter.
NCT04026035 ·Status: COMPLETED
-
Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin
NCT00414362 ·Status: COMPLETED
-
Clinical Performance and Reproducibility of the Accelerate PhenoTest™ Blood Culture (BC) Kit With New Antibiotic Wave I Updates
NCT04295915 ·Status: COMPLETED
-
Catheter Biofilm Microbiome in Infected Neonatal Catheters.
NCT01985737 ·Status: COMPLETED
-
Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes
NCT06069206 ·Status: COMPLETED ·Phase: NA
-
Vancomycin Study: Treatment of Catheter Related Bloodstream Infection Caused by Coagulase Negative Staphylococcus
NCT00175370 ·Status: COMPLETED ·Phase: NA
-
DetectAB - Detecting Antibiotics
NCT03678142 ·Status: COMPLETED
-
Clinical Impact of Fast Phenotypic Antimicrobial Susceptibility Testing on Patients With Gram-Negative Rod Bacteremia
NCT03745014 ·Status: WITHDRAWN ·Phase: NA
-
A Platform Trial for Gram Negative Bloodstream Infections
NCT06537609 ·Status: RECRUITING ·Phase: NA
-
Pharmacokinetics and Pharmacodynamics and Selected Antibiotics During Pregnancy
NCT00214331 ·Status: COMPLETED
-
Pharmacokinetics of Piperacillin/Tazobactam in Patients Treated by Continuous Renal Replacement Therapy
NCT00703144 ·Status: COMPLETED ·Phase: PHASE4
-
Bedside vs. Standard Microbiological Blood Culture Diagnostics - BEMIDIA Study
NCT03000049 ·Status: UNKNOWN
-
Immunosuppression and Intensive Care Unit-acquired Multidrug-resistant Bacteria
NCT06652126 ·Status: RECRUITING
-
Impact of Real-time MIC (Minimum Inhibitory Concentration) Reporting (<6 Hours) on β-lactam Prescription in Cases of Gram-negative Bacilli Bacteremia in ICU Patients in Real-life Settings
NCT07202377 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)
NCT01597973 ·Status: COMPLETED ·Phase: PHASE3
-
Neutrophil Extracellular Traps (NETs) Mediated Killing of Carbapenem-resistant Pseudomonas Aeruginosa.
NCT06441708 ·Status: NOT_YET_RECRUITING
-
Beta-lactam Therapeutic Drug Monitoring in Singapore
NCT04450680 ·Status: UNKNOWN