Copanlisib Plus Venetoclax in R/R DLBCL
NCT04572763 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2026-01-07
Summary
This research study is evaluating the combination of two drugs, copanlisib and venetoclax, as a possible treatment for trelapsed/refractory diffuse large B-cell lymphoma (DLBCL)
The names of the study drugs involved in this study are:
* Copanlisib
* Venetoclax
Conditions
- Diffuse Large B Cell Lymphoma
- Relapsed Diffuse Large B-Cell Lymphoma
- Refractory Diffuse Large B-Cell Lymphoma
Interventions
- DRUG
-
Copanlisib
Intravenous infusion
- DRUG
-
Tablet taken orally
Sponsors & Collaborators
- collaborator INDUSTRY
- collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Jennifer Crombie, MD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-09-08
- Primary Completion
- 2025-07-29
- Completion
- 2026-07-29
- FDA Drug
- Yes
Countries
- United States
Study Locations
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