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Biochemical Pregnancy Loss. A Multicenter Retrospective Study

NCT04549909 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20000

Last updated 2020-09-23

No results posted yet for this study

Summary

Biochemical pregnancy loss (BPL) is a very frequent issue in human reproduction. After the implantation of the embryo, hCG disappears very soon from the maternal bloodstream and no evidence of a clinical pregnancy is seen. Different studies showed that factors such as age, oocyte and embryo quality, and endometrium receptivity may have something to do with the occurrence of biochemical pregnancy loss post assisted reproduction treatment.

The main aim of this study is to evaluate the incidence of biochemical pregnancy loss (BPL) in three different cohort populations; patients undergoing frozen embryo transfer (FET) from own oocytes after preimplantation genetic testing for aneuploidy (PGT-A), patients undergoing FET from own and donated oocytes and with endometrial receptivity array (ERA), and patients undergoing FET from own or donated oocytes (without PGTA or ERA test).

We will analyse the incidence of BPL in these populations and try to determine the role of the euploid status embryo in the first group, the endometrium in the second group and the third one as control group. We are waiting to find the value of both players in the origin of BPL.

Conditions

  • Pregnancy Loss, Early

Interventions

OTHER

collect retrospectively data

Analyse the incidence of BPL in these populations

Sponsors & Collaborators

  • Instituto Valenciano de Infertilidad, IVI VALENCIA

    collaborator OTHER

  • IVI Madrid

    collaborator OTHER

  • Fundación IVI

    collaborator OTHER

  • IVI Vigo

    lead OTHER

Principal Investigators

  • Elkin DR Muñoz, MD · IVI Vigo

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-12
Primary Completion
2020-01-15
Completion
2020-01-15

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04549909 on ClinicalTrials.gov