Persistence of Neutralizing Antibodies 6 and 12 Months After a Covid-19
NCT04543006 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 170
Last updated 2020-09-16
Summary
Covid-19 is associated with the onset of anti-SARS-CoV-2 antibodies; in a majority of patients, neutralizing antibodies are detected. However, the long-term persistence of such protective antibodies is not known.
The investigators will explore patients with a proven Covid-19 (positive PCR) 6 and 12 months after the diagnosis to determine whether neutralizing antibodies are still detected.
The investigators will determine whether this persistance varies according to
* the severity of the Covid-19
* a treatment by steroids during the covid-19. This will help to anticipate whether a second wave of infection is possible in a non-naive population.
Conditions
- Covid19
Interventions
- DIAGNOSTIC_TEST
-
serology
blood sample of 10 ml twice (6 and 12 months after the Covid-19)
Sponsors & Collaborators
-
University Hospital, Grenoble
lead OTHER
Principal Investigators
-
Olivier Epaulard, MD,PhD · University Hospital, Grenoble
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-08
- Primary Completion
- 2021-09-30
- Completion
- 2021-12-31
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