Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel Function
NCT04530383 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-04-15
Summary
The purpose of this study is to assess the efficacy of metformin to improve airway ion channel function in those with CF-related diabetes (CFRD)
Conditions
- Cystic Fibrosis-related Diabetes
- Cystic Fibrosis
Interventions
- DRUG
-
Metformin Hydrochloride
1000 mg twice daily
Sponsors & Collaborators
-
University of Kansas Medical Center
lead OTHER
Principal Investigators
-
Matthias A Salathe, M.D. · Professor
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-02-14
- Primary Completion
- 2027-12-30
- Completion
- 2028-07-15
- FDA Drug
- Yes
Countries
- United States
Study Locations
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