Trial Outcomes & Findings for Computer-Assisted Fixation of Trochanteric Femur Fractures (NCT NCT04528459)

NCT ID: NCT04528459

Last Updated: 2025-03-04

Results Overview

Tip-apex distance of the lag screw in the femoral head as measured on postoperative anteroposterior and lateral x-rays

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

12 participants

Primary outcome timeframe

Immediate post-operative period

Results posted on

2025-03-04

Participant Flow

Participant milestones

Participant milestones
Measure
Traditional Fluoroscopy
Cohort 1 will consist of patients with closed peritrochanteric femur fractures who undergo open reduction internal fixation with a Stryker© Gamma™ cephalomedullary nail using traditional fluoroscopy for insertion of the lag screw (current standard of care).
Stryker© ADAPT™ Platform
Cohort 2 will consist of patients with closed peritrochanteric femur fractures who undergo open reduction internal fixation with a Stryker© Gamma™ cephalomedullary nail using the Stryker© ADAPT™ platform to assist with insertion of the lag screw.
Overall Study
STARTED
6
6
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
6
6

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Computer-Assisted Fixation of Trochanteric Femur Fractures

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Traditional Fluoroscopy
n=6 Participants
Cohort 1 will consist of patients with closed peritrochanteric femur fractures who undergo open reduction internal fixation with a Stryker© Gamma™ cephalomedullary nail using traditional fluoroscopy for insertion of the lag screw (current standard of care).
Stryker© ADAPT™ Platform
n=6 Participants
Cohort 2 will consist of patients with closed peritrochanteric femur fractures who undergo open reduction internal fixation with a Stryker© Gamma™ cephalomedullary nail using the Stryker© ADAPT™ platform to assist with insertion of the lag screw.
Total
n=12 Participants
Total of all reporting groups
Age, Continuous
82.7 years
STANDARD_DEVIATION 12.5 • n=99 Participants
82.0 years
STANDARD_DEVIATION 14.6 • n=107 Participants
82.3 years
STANDARD_DEVIATION 13.0 • n=206 Participants
Sex: Female, Male
Female
4 Participants
n=99 Participants
3 Participants
n=107 Participants
7 Participants
n=206 Participants
Sex: Female, Male
Male
2 Participants
n=99 Participants
3 Participants
n=107 Participants
5 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=99 Participants
0 Participants
n=107 Participants
2 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
4 Participants
n=99 Participants
4 Participants
n=107 Participants
8 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
2 Participants
n=107 Participants
2 Participants
n=206 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Asian
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=99 Participants
1 Participants
n=107 Participants
1 Participants
n=206 Participants
Race (NIH/OMB)
White
6 Participants
n=99 Participants
4 Participants
n=107 Participants
10 Participants
n=206 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
1 Participants
n=107 Participants
1 Participants
n=206 Participants
Region of Enrollment
United States
6 participants
n=99 Participants
6 participants
n=107 Participants
12 participants
n=206 Participants

PRIMARY outcome

Timeframe: Immediate post-operative period

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Tip-apex distance of the lag screw in the femoral head as measured on postoperative anteroposterior and lateral x-rays

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Immediate postoperative period

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Lag screw position in the femoral head/neck as described by Cleveland et al. (1959)

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Intraoperative period

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

The amount of time required to complete the surgical procedure

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Intraoperative period

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

The amount of fluoroscopy utilized during the surgical procedure as measured in seconds

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Intraoperative period

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

The total number of K-wire passes prior to final lag screw placement

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months, 6 months, 1 year, and 2 years after surgery

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Evidence of lag screw cut-out as seen on postoperative hip radiographs

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months, 6 months, 1 year, and 2 years after surgery

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Postoperative range of motion of the affected hip as measured on physical examination

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months, 6 months, 1 year, and 2 years after surgery

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Postoperative patient mobility and social dependency as defined by the Harris Hip Score

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months, 6 months, 1 year, and 2 years after surgery

Population: Data was not collected. Participants were enrolled and randomized prior to the study termination but were not administered the study intervention.

Postoperative pain level as defined by the visual analog scale

Outcome measures

Outcome data not reported

Adverse Events

Traditional Fluoroscopy

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Stryker© ADAPT™ Platform

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Wakenda K. Tyler, MD, MPH

Columbia University

Phone: 2123059192

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place