EGb 761 in the Syndrome of MCI With Concomitant CVD
NCT04525144 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 134
Last updated 2022-11-17
Summary
EGb 761 has been demonstrated to be useful in improving cognitive and global clinical outcomes in patients with cognitive impairment or dementia, when administered at a daily dosage of 240mg in randomised controlled trials through several neuroprotective mechanisms of action. The study aims to determine the efficacy and safety profile of EGb 761 as a prescribed clinical drug for patients with MCI + CVD.
Conditions
- Mild Cognitive Impairment
- Cerebrovascular Disease
Interventions
- DRUG
-
Tebonin Forte
Dietary supplement: Gingko biloba EGb 761
Sponsors & Collaborators
-
Dr. Willmar Schwabe GmbH & Co. KG
collaborator INDUSTRY -
National Neuroscience Institute
lead OTHER
Principal Investigators
-
Kok Pin Ng · National Neuroscience Institute
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 45 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-10-26
- Primary Completion
- 2025-12-31
- Completion
- 2026-11-30
Countries
- Singapore
Study Locations
More Related Trials
-
Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI
NCT01046292 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients
NCT03514875 ·Status: WITHDRAWN ·Phase: NA
-
Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease
NCT03486938 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Clinical Trial of AGB101 for Mild Cognitive Impairment
NCT05986721 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints
NCT00276510 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)
NCT06347315 ·Status: RECRUITING ·Phase: NA
-
Investigating the Efficacy of Ergothioneine to Delay Cognitive Decline (Pilot)
NCT03641404 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease
NCT04971733 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Efficacy of DL-NBP in Patients With Mild Subcortical Ischemic Vascular Dementia
NCT03906123 ·Status: UNKNOWN ·Phase: NA
-
Study of the Effect of SR57667B in Patients With Alzheimer's Disease
NCT00285025 ·Status: COMPLETED ·Phase: PHASE2
-
A Safety and Tolerability Study of GB301
NCT03865017 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of CM383 in Patients With Alzheimer's Disease Related Mild Cognitive Impairment and Mild Alzheimer's Disease
NCT06619613 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
NCT07169578 ·Status: RECRUITING ·Phase: PHASE3
-
BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)
NCT02502253 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation the Effect of Acetyl-L-carnitine in Patients With Mild Cognitive Impairment Accompanied With Chronic Cerebrovascular Disease
NCT04346862 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy and Safety of TMBCZG in Mild to Moderate Vascular Dementia
NCT03230071 ·Status: COMPLETED ·Phase: PHASE2
-
ANAVEX2-73 for Treatment of Early Alzheimer's Disease
NCT03790709 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study of NTRX-07 in Participants With Alzheimer's Disease
NCT07058688 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
NCT06976216 ·Status: RECRUITING ·Phase: PHASE3
-
EEG (Electroencephalogram) Platform Standardization in Healthy Male Subjects (3134-010)
NCT01110616 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
NCT02423200 ·Status: COMPLETED ·Phase: PHASE2
-
Network-Level Mechanisms for Preclinical Alzheimer's Disease Development
NCT03461861 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment
NCT02573740 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Assess THN391 in Subjects With Alzheimer's Disease
NCT06814730 ·Status: RECRUITING ·Phase: PHASE1
-
Safety and Efficacy of MT-4666
NCT01764243 ·Status: COMPLETED ·Phase: PHASE2