Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy

Summary

When delivered online, behavioral obesity treatments have the potential to reach large numbers of individuals with overweight/obesity and produce significant improvements in health and wellbeing. In order to maximize the public health benefit of disseminating these treatments online, this study will use the Multiphase Optimization Strategy (MOST) framework to most quickly and efficiently determine which, if any, of 5 innovative intervention components, alone or in combination, increases the proportion of patients achieving a ≥5% weight loss, and mean weight loss, after a 12-month online behavioral obesity treatment.

Conditions

• Overweight and Obesity

Interventions

BEHAVIORAL

Online Behavioral Weight Loss Program

A self-guided, online program that helps participants reduce energy intake and gradually increase physical activity.

BEHAVIORAL

Virtual Reality for Behavioral Weight Loss Skills Training

This program allows participants to practice behavioral weight loss skills using an online virtual reality system accessed via a Web browser.

BEHAVIORAL

Tailored Interactive Video Feedback

Video-recorded messages are used to provide periodic feedback on progress with weight loss, dietary change, and physical activity. Additional videos provide dietary skills training.

BEHAVIORAL

Tailored Intervention for Structured Physical Activity

Periodic self-assessment is used to guide selection of a physical activity goal. Home-based instructional videos are provided to help meet the selected goal.

BEHAVIORAL

Skills Training for Dysregulated Eating

Periodic self-assessment is used to guide selection of skills training modules designed to counter common causes of dysregulated eating (e.g., boredom, stress).

BEHAVIORAL

Platform for Social Support & Friendly Competition

An online platform is provided for participants to connect with each other, support each other, and compete on achievement of behavioral and weight loss milestones.

Sponsors & Collaborators

• The Miriam Hospital

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-09-22

Primary Completion

2023-05-18

Completion

2023-05-18

Countries

• United States

Study Locations