Perioperative Lactate Kinetics in Patient Undergoing Major Liver Surgery
NCT04512014 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55
Last updated 2020-08-13
Summary
Major liver surgery is associated with increased incidence of perioperative complications and increased mortality if these are not addressed quickly in a high dependency intensive care unit. Of these, posthepatectomy liver failure (PHLF) represents one of the most important cause of postoperative unfavourable outcome. The present study investigates the correlation between lactate levels and PHLF. Lactate levels were collected at six specific timepoints: preoperative, pre-dissection phase, post-dissection phase, end of surgery and 24-hours and 48-hours in the postoperative period.
Conditions
- Liver Failure, Acute
Interventions
- DIAGNOSTIC_TEST
-
serum lactate
perioperative measurement of lactate levels
Sponsors & Collaborators
-
Institutul Clinic Fundeni
lead OTHER
Principal Investigators
-
Dana Tomescu, Prof · Fundeni Clinical Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-01
- Primary Completion
- 2019-12-31
- Completion
- 2019-12-31
Countries
- Romania
Study Locations
More Related Trials
-
Remote Ischemic Preconditioning in Cardiac Surgery
NCT04647370 ·Status: UNKNOWN ·Phase: NA
-
Perioperative Blood Transfusion in Open Liver Resection
NCT06189911 ·Status: COMPLETED
-
Prognostic Value of Peak Lactate During Cardiopulmonary Bypass in Adult Cardiac Surgeries
NCT03934892 ·Status: COMPLETED
-
The Influence of Preoperative Cardiopulmonary Capacity on the Perioperative Lactate Level
NCT01819337 ·Status: COMPLETED
-
Restrictive vs Goal Directed Fluid Therapy During Hepatobiliary Surgery
NCT04092608 ·Status: COMPLETED ·Phase: NA
-
Magnesium Administration in Liver Transplantation and Reperfusion Injury
NCT00994981 ·Status: COMPLETED ·Phase: PHASE4
-
Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event
NCT03344224 ·Status: COMPLETED
-
Echocardiographic Assessment of Volume Variation Secondary to Preoperative Fasting
NCT01258361 ·Status: COMPLETED
-
Observational Study on the Clinical Impact of Desaturation During Liver Surgery
NCT01458262 ·Status: COMPLETED
-
Evaluation of Hemodynamics and Amount of Blood Flowing Through the Kidneys During Liver Transplant by Measuring Some Physiological Substances in Blood and Urines
NCT01650116 ·Status: UNKNOWN
-
Effect of Prone Position on Liver Blood Flow and Function
NCT01781260 ·Status: UNKNOWN
-
NEW MONITORING IN DIFFERENTIAL DIAGNOSIS OF HYPERLACTATHEMIA IN CARDIOPULMONARY BYPASS SURGERY
NCT04706884 ·Status: COMPLETED
-
Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery
NCT06292910 ·Status: COMPLETED
-
The Validity of Central Venous to Arterial Co2 Difference During Living Donor Liver Transplantation
NCT03123172 ·Status: COMPLETED ·Phase: NA
-
Parasternal Blockade and Serum Lactate in Cardiac Surgery
NCT06516432 ·Status: RECRUITING ·Phase: NA
-
Cardiac Output Optimization on Postoperative Complications in Major Hepatic Surgery
NCT04655885 ·Status: RECRUITING ·Phase: NA
-
Early Extubation and Postoperative Complications After Liver Transplantation
NCT04261816 ·Status: COMPLETED
-
Paraesternal Blockade and Lactate Serum Levels in Patients with Cardiac Surgery.
NCT06608290 ·Status: COMPLETED ·Phase: PHASE3
-
Portal Inflow Modulation Prior to Liver Transplantation in Patients With Increased Risk of Intraoperative Blood Loss
NCT07111221 ·Status: RECRUITING ·Phase: NA
-
Ischemic Preconditioning. Prospective Comparison
NCT01432548 ·Status: UNKNOWN ·Phase: NA
-
Estimated Blood Loss: Novel Model for Estimating Surgical Blood Loss.
NCT03249038 ·Status: COMPLETED
-
Postoperative Supplemental Oxygen in Liver Transplantation
NCT02857855 ·Status: UNKNOWN ·Phase: NA
-
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes
NCT05052619 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Corrected Carotid Flow Time Variations During Passive Leg Lift to Predict Response to Filling.
NCT04732481 ·Status: COMPLETED
-
Fluid Optimisation in Laparoscopic Colorectal Procedures
NCT04719884 ·Status: COMPLETED ·Phase: NA