Methylation Analysis of Circulating Tumor DNA in Gastric Cancer
NCT04511559 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 540
Last updated 2020-08-13
Summary
The primary purpose of this trial is to describe the profile of ctDNA methylation in gastric cancer. The second purpose is to demonstrate the correlation between the plasma ctDNA methylation status and the diagnosis and prognosis of patients with early and intermediate stage gastric cancer.
Conditions
- Stomach Neoplasms
- Circulating Tumor DNA
Interventions
- DIAGNOSTIC_TEST
-
Circulating Tumor DNA Methylation Sequencing
Whole blood collection through venipuncture. DNA methylation levels by deep sequencing.
- DIAGNOSTIC_TEST
-
tissue DNA Methylation Sequencing
Isolate DNA from tissue samples from subjects. DNA methylation levels by deep sequencing.
Sponsors & Collaborators
-
Shanghai Zhongshan Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-10-01
- Primary Completion
- 2023-09-30
- Completion
- 2025-05-01
More Related Trials
-
Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer
NCT05497739 ·Status: UNKNOWN ·Phase: PHASE2
-
Plasma Metabolic Biomarkers for Gastric Cancer Diagnosis
NCT06109805 ·Status: COMPLETED
-
A Multi-omics-based Metabolic Typing Study of Gastric Cancer
NCT06134011 ·Status: ACTIVE_NOT_RECRUITING
-
Genotype-drive Study of Irinotecan-Cisplatin Combination for Advanced Gastric Cancer
NCT01444521 ·Status: COMPLETED ·Phase: PHASE2
-
Transcriptomic Signatures in Gastric Adenocarcinoma
NCT05319392 ·Status: UNKNOWN
-
Metabolomic and Lipidomic Analysis Predicts Immunotherapy-related Adverse Events in Gastric Cancer Patients
NCT06915389 ·Status: RECRUITING
-
Relationship Between Standard Treatment Efficacy and The Tumor Microenvironment in Advanced Gastric Cancer
NCT04850716 ·Status: UNKNOWN
-
Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer
NCT06157216 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Safety and Efficacy of G17DT Immunogen in the Treatment of Gastric and Gastroesophageal Cancer
NCT00042510 ·Status: COMPLETED ·Phase: PHASE2
-
First-Line and Neoadjuvant Immunotherapy for Gastric Cancer
NCT06727981 ·Status: RECRUITING
-
Microbiota and Metabolomics of Intestinal Type of Gastric Cancer
NCT06079554 ·Status: RECRUITING
-
Genomic Evolution of Metastasis in Gastric Cancer
NCT05061082 ·Status: UNKNOWN
-
Transarterial Chemoembolization With Lipiodol in the Treatment of Initial Unresectable Gastric Cancer (GC)
NCT05361161 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Albumin Bound Paclitaxel Plus S-1 as the First Line Chemotherapy in Advanced or Recurrent Gastric Cancer
NCT02229058 ·Status: COMPLETED ·Phase: PHASE2
-
Using Genetic Polymorphisms to Predict the Efficacy and Toxicity - A Gastric Adenocarcinoma Study
NCT01558011 ·Status: TERMINATED ·Phase: PHASE2
-
Drug Sensitivity Screening for Gastrointestinal Cancer
NCT04298489 ·Status: UNKNOWN ·Phase: NA
-
Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy Evaluation of GST-HG161
NCT04228406 ·Status: UNKNOWN ·Phase: PHASE1
-
Effect of Adjuvant Chemotherapy Cycles on Patients With Node-negative Gastric Cancer Following Neoadjuvant Chemotherapy
NCT06277453 ·Status: ACTIVE_NOT_RECRUITING
-
Establishment of Serum Proteomics Subtypes of Gastric Cancer and Its Clinical Application
NCT06335576 ·Status: NOT_YET_RECRUITING
-
A Pilot Study of Crizotinib in Patients With c-MET Positive Gastric Adenocarcinoma as a Third-line Chemotherapy
NCT02435108 ·Status: COMPLETED ·Phase: PHASE2
-
A Trail of CDK4 / 6 Inhibitor and MEK Inhibitor in the Treatment of Metastatic Digestive System Tumors
NCT04615312 ·Status: UNKNOWN ·Phase: PHASE1
-
Real World Study of Immune Checkpoint Inhibitors for Advanced Gastric Cancer
NCT04086888 ·Status: UNKNOWN
-
Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.
NCT07188441 ·Status: RECRUITING ·Phase: PHASE2
-
Financial Incentives and Motivational Intervention to Improve Gastric Cancer Screening in China
NCT06384300 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Application Value of CTCs Detection for Advanced Gastric Cancer Patients
NCT03156777 ·Status: UNKNOWN