Early Detection of CMP in Patients With Breast Cancer Using Cardiac Magnetic Resonance
NCT04510532 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2023-06-01
Summary
Breast cancer is the most common cancers among women worldwide.Although chemotherapy and surgery have greatly improved the survival rate, most types of chemotherapy have been reported to have varying degrees of cardiotoxicity. The investigators will focus on the cardiotoxicity of pyrotinib and apatinib which belong to the new tyrosine kinase inhibitors in respective chemotherapy among more subjects.
Conditions
- Breast Cancer
- Chemotherapy Induced Systolic Dysfunction
Interventions
- DIAGNOSTIC_TEST
-
CMR examination
After recruiting participants and collecting the baseline information, a CMR scan and a post-processed imaging procedure will be carried on .And the follow-up is planned at 1,6 months after chemotherapy in order to detect the cardiac impairment
Sponsors & Collaborators
-
Ruijin Hospital
collaborator OTHER -
Shanghai Fifth People's Hospital
collaborator UNKNOWN -
RenJi Hospital
lead OTHER
Principal Investigators
-
Meng Jiang, MD · RenJi Hospital, School of Medicine, Shanghai Jiantong University
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-10-30
- Primary Completion
- 2023-09-30
- Completion
- 2023-09-30
Countries
- China
Study Locations
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