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The Use of Biochemical Analyzes to Monitor the Development of Wounds

NCT04507724 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2021-05-18

No results posted yet for this study

Summary

Chronic wounds represent a growing challenge in medical care.

Part 1: The aim of this part of the study was to collect wound swabs and to answer the question whether the rapid diagnostic tool using enzyme activities can display an infection prematurely. This means that an increased enzyme activity (especially MPO, NHE, LYS, gelatinase, pH) measured overed 3 days, would indicate a change in the wound bed (infection, Inflammation) earlier than the regularly performed clinical assessment.

Part 2: The aim of this part of the study was to evaluate (I) the possibility of wound fluid acquisition by means of an "additional collector" during ongoing NPWT and to answer if (II) this secretion can be biochemically analyzed for enzyme activities in order to be able to detect a change in the wound situation at an early stage.

Conditions

  • Wound
  • Wound Infection
  • Wound Contamination
  • Diagnostic Techniques and Procedures
  • Negative Pressure Wound Therapy
  • Biomarker

Sponsors & Collaborators

  • Qualizyme Diagnostics GmbH & Co KG

    lead INDUSTRY

Principal Investigators

  • Michael Schintler, Prof. · Medical University of Graz

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-19
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04507724 on ClinicalTrials.gov