Trial Outcomes & Findings for Evaluation of the LipiFlow System With a New Activator (NCT NCT04500821)

NCT ID: NCT04500821

Last Updated: 2022-01-24

Results Overview

Evaluation of the clinical use of the LipiFlow system with the Activator LFD-2100

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

44 participants

Primary outcome timeframe

1 day after completion of LipiFlow treatment

Results posted on

2022-01-24

Participant Flow

A total of 88 eyes of 44 subjects with meibomian gland dysfunction were enrolled.

Unit of analysis: Eyes

Participant milestones

Participant milestones
Measure
Activator LFD-2100
Lipiflow treatment with Activator LFD-2100
Overall Study
STARTED
44 88
Overall Study
COMPLETED
44 88
Overall Study
NOT COMPLETED
0 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluation of the LipiFlow System With a New Activator

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Activator LFD-2100
n=44 Participants
Lipiflow treatment with Activator LFD-2100
Age, Customized
< 30 years
0 Participants
n=99 Participants
Age, Customized
30-39 years
0 Participants
n=99 Participants
Age, Customized
40-49 years
1 Participants
n=99 Participants
Age, Customized
50-59 years
6 Participants
n=99 Participants
Age, Customized
60-69 years
19 Participants
n=99 Participants
Age, Customized
>= 70 years
18 Participants
n=99 Participants
Sex: Female, Male
Sex · Female
31 Participants
n=99 Participants
Sex: Female, Male
Sex · Male
13 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Ethnicity · Hispanic or Latino
3 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Ethnicity · Not Hispanic or Latino
41 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Ethnicity · Unknown or Not Reported
0 Participants
n=99 Participants
Race/Ethnicity, Customized
Asian
2 Participants
n=99 Participants
Race/Ethnicity, Customized
Black
0 Participants
n=99 Participants
Race/Ethnicity, Customized
Native Hawaiian/Pacific Islander
0 Participants
n=99 Participants
Race/Ethnicity, Customized
Caucasian
42 Participants
n=99 Participants

PRIMARY outcome

Timeframe: 1 day after completion of LipiFlow treatment

Population: All treated eyes

Evaluation of the clinical use of the LipiFlow system with the Activator LFD-2100

Outcome measures

Outcome measures
Measure
Activator LFD-2100
n=88 Eyes
LipiFlow treatment with Activator LFD-2100
Successful Completion of LipiFlow Treatment With Activator LFD-2100
100 Percent of eyes
Interval 96.0 to 100.0

Adverse Events

Right Eye (OD)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Left Eye (OS)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Luis Vargas, MD

Johnson & Johnson Surgical Vision

Phone: 714-247-8200

Results disclosure agreements

  • Principal investigator is a sponsor employee The sponsor must review results communication prior to public release and can embargo communications regarding trial results at anytime.
  • Publication restrictions are in place

Restriction type: OTHER