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Assessment of Subsynovial Connective Tissue Thickness in Carpal Tunnel Syndrome

NCT04491058 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 92

Last updated 2025-02-21

No results posted yet for this study

Summary

The general aim of this research is to gain insight in the role of SSCT in the etiology and progression of CTS. We hypothesize that (degenerative) damage of the SSCT occurs early on in the pathogenesis of CTS. Fibrotic damage to the SSCT will lead to altered morphology and biomechanical characteristics. This eventually may lead to damage of the median nerve. To examine the SSCT an ultrasound technique described by Van Doesburg et al. 2012 will be used First, the reliability of the US technique to characterize morphology of the SSCT will be investigated. Secondly, cross-sectional data will be collected in healthy subjects and CTS patients to provide descriptive parameters and to describe differences between patients and controls. In the final part a prospective study will be conducted to look at changes of SSCT thickness over time and after treatment.

Conditions

  • Carpal Tunnel Syndrome

Interventions

DIAGNOSTIC_TEST

SSCT thickness measurement

Thickness measurement with ultrasound

Sponsors & Collaborators

  • KU Leuven

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-08-11
Primary Completion
2024-05-06
Completion
2024-05-06

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04491058 on ClinicalTrials.gov