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RESIST-ADT (Androgen Deprivation Therapy)

NCT04485767 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2024-08-20

No results posted yet for this study

Summary

The overall goal of this study is to determine if implementing structured exercises prevent decline in muscle mass, muscle strength and physical function in men with prostate cancer undergoing androgen deprivation therapy (ADT). Our main hypothesis is that structured resistance exercise training in men undergoing ADT will preserve physical function assessed by loaded stair climbing power compared with the control group. The trial will also examine the efficacy of the exercise regimen on muscle strength, QOL and fatigue. The findings of this trial will lay the groundwork for definitive intervention trials to prevent frailty and falls in these men.

Conditions

Interventions

BEHAVIORAL

Progressive Resistance Training Exercise

Progressive Resistance Training Exercise 2x weekly for 6 months.

BEHAVIORAL

Flexibility and Balance Exercise

Flexibility and Balance Exercise Training Exercise 2x weekly for 6 months.

Sponsors & Collaborators

Principal Investigators

  • Shehzad Basaria, MD · Brigham and Women's Hospital

  • Thomas Storer, PhD · Brigham and Women's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2023-09-30
Completion
2023-09-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04485767 on ClinicalTrials.gov