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Puberty Suppression and Cardiometabolic Health

NCT04482374 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2025-06-10

No results posted yet for this study

Summary

This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin releasing hormone agonist compared to matched cisgender male controls.

Conditions

  • Transgenderism
  • Insulin Sensitivity/Resistance
  • Endothelial Dysfunction
  • Vascular Stiffness

Sponsors & Collaborators

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Natalie J Nokoff, MD, MSCS · University of Colorado, Denver

Eligibility

Min Age
9 Years
Max Age
14 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-10
Primary Completion
2026-07-31
Completion
2026-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04482374 on ClinicalTrials.gov