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Total Knee Arthroplasty and Clinical Findings

NCT04481711 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2020-07-24

No results posted yet for this study

Summary

Knee osteoarthritis is a common disease that causes pain and loss of function. Total Knee Arthroplasty (TKA) is a frequently used surgical method in the treatment of severe knee osteoarthritis. The aim of this study was to investigate the effect of TKA on IL-6, TNF-α and IL-1β cytokine levels, pain intensity at rest and walking, knee joint valgity angle,malaligment, functional status and knee joint position sense.

Conditions

  • Orthopedic Disorder
  • Arthropathy of Knee
  • Pain, Joint
  • Proprioception
  • Radiography

Interventions

PROCEDURE

Total Knee Arthroplasty

Osteoarthritis (OA) is one of the most common chronic peripheral joint diseases increasing among the aging population.Pathogenesis is not fully known.One of the most common risk factors and causes are loss of pain and function. Knee joint osteoarthritis adversly affects the person's life quality. Total Knee Arthroplasty (TKA) is a surgical approach to restore tibiofemoral joint alignment, especially in the severe level of knee OA.

Sponsors & Collaborators

  • Karadeniz Technical University

    lead OTHER

Principal Investigators

  • Murat Emirzeoğlu · Karadeniz Technical University

  • Arzu Erden · Karadeniz Technical University

  • Kübra Canlı · Hacettepe University

  • Serap Özer Yaman · Karadeniz Technical University

  • İbrahim Pekşen · Karadeniz Technical University

  • Osman Aynacı · Karadeniz Technical University

  • Süleyman Caner Karahan · Karadeniz Technical University

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-08
Primary Completion
2020-02-08
Completion
2020-05-08

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04481711 on ClinicalTrials.gov