Trial Outcomes & Findings for Post-endodontic Pain Survey (NCT NCT04462731)

NCT ID: NCT04462731

Last Updated: 2020-10-01

Results Overview

Patients were asked to rate the intensity of preoperative pain on a visual analogue scale (VAS) from 0 (no pain) to 10 (worst pain ever) before receiving root canal treatment. At the end of the visit, the patients were given a survey and asked to rate the intensity of postoperative pain (VAS 0-10) at 4 hours, 24 hours, and 48 hours after the procedure.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

194 participants

Primary outcome timeframe

4-, 24-, and 48-hour after receiving root canal treatment

Results posted on

2020-10-01

Participant Flow

Only recruited irreversible pulpitis cases that received single-visit root canal treatment.

Participant milestones

Participant milestones
Measure
Obturation Technique: WVT
Warm vertical compaction technique (WVT): Teeth filled with AH Plus Jet Root Canal Sealer were filled with .04 taper gutta-percha points by WVT. The sealer was introduced with the master cone. The depth of heated plugger was within 3-5 mm of WL in the WVT group, and the remaining canal space was backfilled with additional sealer and thermoplasticized gutta-percha.
Obturation Technique: SBT
Sealer-based filling technique (SBT): Teeth filled with SBT were obturated with EndoSequence BC Sealer by injecting the sealer into the coronal third of each canal. Size 30 Lentulo spiral coated with additional sealer was introduced 3 mm short of WL depth at 300rpm. Bioceramic coated gutta-percha was dipped in BC sealer and introduced into the canal to WL. A heated plugger was used to sear the gutta-percha point at each orifice.
Overall Study
STARTED
97
97
Overall Study
COMPLETED
41
51
Overall Study
NOT COMPLETED
56
46

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Obturation Technique: WVT
n=41 Participants
Warm vertical compaction technique (WVT): Teeth filled with AH Plus Jet Root Canal Sealer were filled with .04 taper gutta-percha points by WVT. The sealer was introduced with the master cone. The depth of heated plugger was within 3-5 mm of WL in the WVT group, and the remaining canal space was backfilled with additional sealer and thermoplasticized gutta-percha.
Obturation Technique: SBT
n=51 Participants
Sealer-based filling technique (SBT): Teeth filled with SBT were obturated with EndoSequence BC Sealer by injecting the sealer into the coronal third of each canal. Size 30 Lentulo spiral coated with additional sealer was introduced 3 mm short of WL depth at 300rpm. Bioceramic coated gutta-percha was dipped in BC sealer and introduced into the canal to WL. A heated plugger was used to sear the gutta-percha point at each orifice.
Total
n=92 Participants
Total of all reporting groups
Age, Continuous
46.2 years
STANDARD_DEVIATION 14.4 • n=41 Participants
46.7 years
STANDARD_DEVIATION 16.6 • n=51 Participants
46.5 years
STANDARD_DEVIATION 15.6 • n=92 Participants
Sex: Female, Male
Female
30 Participants
n=41 Participants
34 Participants
n=51 Participants
64 Participants
n=92 Participants
Sex: Female, Male
Male
11 Participants
n=41 Participants
17 Participants
n=51 Participants
28 Participants
n=92 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.

PRIMARY outcome

Timeframe: 4-, 24-, and 48-hour after receiving root canal treatment

Population: The data from all 92 survey was included for analysis.

Patients were asked to rate the intensity of preoperative pain on a visual analogue scale (VAS) from 0 (no pain) to 10 (worst pain ever) before receiving root canal treatment. At the end of the visit, the patients were given a survey and asked to rate the intensity of postoperative pain (VAS 0-10) at 4 hours, 24 hours, and 48 hours after the procedure.

Outcome measures

Outcome measures
Measure
Obturation Technique: WVT
n=41 Participants
Warm vertical compaction technique (WVT): Teeth filled with AH Plus Jet Root Canal Sealer were filled with .04 taper gutta-percha points by WVT. The sealer was introduced with the master cone. The depth of heated plugger was within 3-5 mm of WL in the WVT group, and the remaining canal space was backfilled with additional sealer and thermoplasticized gutta-percha.
Obturation Technique: SBT
n=51 Participants
Sealer-based filling technique (SBT): Teeth filled with SBT were obturated with EndoSequence BC Sealer by injecting the sealer into the coronal third of each canal. Size 30 Lentulo spiral coated with additional sealer was introduced 3 mm short of WL depth at 300rpm. Bioceramic coated gutta-percha was dipped in BC sealer and introduced into the canal to WL. A heated plugger was used to sear the gutta-percha point at each orifice.
Visual Analogue Scale (VAS)
Preoperative
4.06 score on a scale
Interval 2.95 to 5.17
2.68 score on a scale
Interval 1.9 to 3.45
Visual Analogue Scale (VAS)
Postoperative 4-hour
2.41 score on a scale
Interval 1.74 to 3.09
2.27 score on a scale
Interval 1.65 to 2.94
Visual Analogue Scale (VAS)
Postoperative 24-hour
1.95 score on a scale
Interval 1.27 to 2.63
1.8 score on a scale
Interval 1.14 to 2.49
Visual Analogue Scale (VAS)
Postoperative 48-hour
1.15 score on a scale
Interval 0.6 to 1.7
1.00 score on a scale
Interval 0.54 to 1.46

Adverse Events

Obturation Technique: WVT

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Obturation Technique: SBT

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Ya-Hsin Yu

University of Pennsylvania

Phone: 215-898-4927

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place