Anti-rheumatic Drug Use and Risk of COVID-19 Infection in Rheumatoid Arthritis Patients
NCT04434118 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2022-05-09
Summary
Rheumatoid arthritis (RA) patients have an underlying immune deficiency and typically treated with immunosuppressive drugs, which may increase the risk of COVID-19 infection. Hydroxychloroquine (HCQ) has been found to possess antiviral activity against COVID-19. Thus, the aim of this study to investigate the ability of HCQ to reduce the risk of COVID-19 among RA patients.
Conditions
Interventions
- DRUG
-
Traditional antirheumatic drugs
Hydroxychloroqine, Methotrexate, Glucocorticoids, Leflunomide, and Sulphasalazine
Sponsors & Collaborators
-
Sadat City University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-20
- Primary Completion
- 2021-12-30
- Completion
- 2021-12-30
Countries
- Egypt
Study Locations
More Related Trials
-
IMPACT: IMPact of Antimalarials on Covid-19 Infections in RAPPORT
NCT04347798 ·Status: COMPLETED
-
Efficacy, Tolerability and Safety Study in Rheumatoid Arthritis (0812-008)
NCT00542022 ·Status: COMPLETED ·Phase: PHASE2
-
Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants
NCT04426279 ·Status: TERMINATED
-
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
NCT07048197 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
SarS-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism
NCT04584541 ·Status: TERMINATED ·Phase: NA
-
COVID-19 Vaccination in Rheumatic Disease Patients
NCT04839315 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Study To Investigate And Describe The Treatment Patterns And Effect Of Tofacitinib Indicators For Patients With Rheumatoid Arthritis
NCT04721808 ·Status: COMPLETED
-
Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy
NCT04532372 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study To Compare The Effectiveness Of Tofacitinib 11 Mg Once A Day To Tofacitinib 5 Mg Twice A Day
NCT04267380 ·Status: COMPLETED
-
COVID-19 Vaccination in Patients With Rheumatic Diseases
NCT04845997 ·Status: UNKNOWN
-
Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid Arthritis
NCT02644499 ·Status: COMPLETED ·Phase: PHASE4
-
The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment
NCT03855007 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Tolerability of NNC0141-0000-0100 in Subjects With Rheumatoid Arthritis
NCT01370902 ·Status: COMPLETED ·Phase: PHASE1
-
Treatments Against RA and Effect on FDG-PET/CT
NCT02374021 ·Status: COMPLETED ·Phase: PHASE4
-
Identification of Factors Associated With the Occurrence of Severe Forms of COVID-19 Infection in Patients With Inflammatory Rheumatism or Autoimmune Diseases
NCT05026892 ·Status: UNKNOWN
-
Interleukin-6 Inhibitors and Drug-drug Interactions in Patients With Rheumatoid Arthritis
NCT04842981 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Treatment of Rheumatoid Arthritis With Roxithromycin
NCT00439062 ·Status: COMPLETED ·Phase: PHASE4
-
An Oral p38 Inhibitor Investigating Safety, Efficacy, And PK In Subjects With Active Rheumatoid Arthritis
NCT00383188 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis
NCT00848120 ·Status: COMPLETED ·Phase: PHASE3
-
Study Of The Safety Of CE 224,545 And Methotrexate In Patients With Rheumatoid Arthritis
NCT00446784 ·Status: COMPLETED ·Phase: PHASE1
-
COVID-SErology in Rheumatoid Arthritis (COVID-19)
NCT04407559 ·Status: COMPLETED
-
COVID-19 Vaccine in Immunosuppressed Adults With Autoimmune Diseases
NCT04806113 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Trial Evaluating Methotrexate or Leflunomide + Targeted Therapy Versus Methotrexate or Leflunomide + Sulfasalazine + Hydroxychloroquine in Patients With Rheumatoid Arthritis and Insufficient Response to Methotrexate or Leflunomide
NCT02714634 ·Status: RECRUITING ·Phase: PHASE4
-
Patients With Rheumatoid Arthritis (RA) Treated With Rituximab in Kuopio University Hospital
NCT00854321 ·Status: COMPLETED
-
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases
NCT01151644 ·Status: UNKNOWN ·Phase: PHASE4