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Evaluating Cascade Communication Methods

NCT04428736 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2026-04-16

No results posted yet for this study

Summary

Hereditary cancer programs face challenges with respect to effective communication of genetic test results within families and uptake of genetic testing by relatives. This study aims to determine if a "disclosure toolkit" provided to the index participant (carrier of cancer risk gene mutation) contributes to sharing genetic test results with relatives, if there are preferred disclosure methods, and whether toolkit use contributes towards at-risk relatives pursuing genetic testing.

Conditions

  • BRCA1 Mutation
  • BRCA2 Mutation

Interventions

BEHAVIORAL

Disclosure Toolkit

Participants will receive a "Disclosure Toolkit" consisting of a family letter, gene information chatbot, and informational website to aid in communicating their genetic test results with at-risk relatives.

Sponsors & Collaborators

Principal Investigators

  • Susan M Domchek, MD · Penn Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-19
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04428736 on ClinicalTrials.gov