Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study
NCT04412876 · Status: WITHDRAWN · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2022-08-17
Summary
To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women
Conditions
- Stress Urinary Incontinence
Interventions
- DRUG
-
Duloxetine
Duloxetine 30 mg qd
- DRUG
-
Imipramine
Imipramine 25mg qd
Sponsors & Collaborators
-
Far Eastern Memorial Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-05-31
- Primary Completion
- 2020-05-31
- Completion
- 2021-06-03
Countries
- Taiwan
Study Locations
More Related Trials
-
Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence
NCT00190567 ·Status: COMPLETED ·Phase: PHASE2
-
Risk Factors for Treatment Failure in Women With Detrusor Overactivity Receiving Combined Pharmacotherapy
NCT07337252 ·Status: COMPLETED
-
Duloxetine Stress Urinary Incontinence Efficacy and Safety Study
NCT00475397 ·Status: COMPLETED ·Phase: PHASE3
-
To Evaluate the Safety of Duloxetine in Patients With Stress Urinary Incontinence
NCT00190645 ·Status: COMPLETED ·Phase: PHASE3
-
Open Label Phase III Duloxetine Study for Stress Urinary Incontinence
NCT00191204 ·Status: COMPLETED ·Phase: PHASE3
-
To Evaluate the Safety in Patients Taking Duloxetine for Stress Urinary Incontinence
NCT00190632 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluate Safety and Efficacy of Duloxetine in Predominant Stress Urinary Incontinence
NCT00190996 ·Status: COMPLETED ·Phase: PHASE3
-
Urge Incontinence Bladder Overactivity Study
NCT00475696 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Effectiveness Study of Duloxetine HCl in Women of Different Backgrounds With Stress Urinary Incontinence Who May Also Have Other Various Medical Conditions.
NCT00190905 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
NCT00780832 ·Status: TERMINATED ·Phase: NA
-
A Therapeutic Exploratory Clinical Study of DA-8010 in Patients With Overactive Bladder
NCT03566134 ·Status: COMPLETED ·Phase: PHASE2
-
Studies of Psychiatric Predisposing Factors, Treatment-related Cardiovascular Effects, and Prognostic Factors Associated With Antimuscarinic Drug (Tolterodine) for Female Overactive Bladder Syndrome
NCT01503580 ·Status: COMPLETED ·Phase: NA
-
A Phase 2, Randomized, Placebo-controlled, Double-blind Study of EG017 in Female Patients With Stress Urinary Incontinence
NCT05674045 ·Status: COMPLETED ·Phase: PHASE2
-
Post-treatment Novmalized Urodynamiz Findings as the Golden Standard of Objective Cure for Female Overactive Bladder Patients Receiving Antimuscarinic Drug
NCT01627145 ·Status: UNKNOWN ·Phase: NA
-
Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.
NCT01282840 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Duloxetine
NCT00190619 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy Subjects
NCT02821312 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Efficacy Study of a New Treatment for Symptoms of Urinary Incontinence
NCT01340066 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of OROS Oybutynin and TTS Oxybutynin in Middle-Aged and Elderly Women With Urinary Incontinence
NCT00304499 ·Status: COMPLETED ·Phase: PHASE3
-
Exploratory Study Evaluating the Effects of Darifenacin on Nocturia, Sleep and Daytime Wakefulness
NCT01018225 ·Status: WITHDRAWN ·Phase: PHASE4
-
Flexibly adding-on Second Antimuscarinic Agent to the First Antimuscarinics for Refractory Overactive Bladder Syndrome
NCT01824420 ·Status: COMPLETED ·Phase: PHASE4
-
Investigation of the Superiority Effect of Desmopressin to Placebo in Terms of Night Voids Reduction in Nocturia Adult Female Patients
NCT01223937 ·Status: COMPLETED ·Phase: PHASE3
-
Inflammation in Women With Urgency Urinary Incontinence Treated With Anticholinergics
NCT04090190 ·Status: COMPLETED ·Phase: PHASE4
-
Therapeutic Efficacy and Safety of Mirabegron Treatment on Patients With Overactive Bladder Syndrome in Taiwan
NCT03044912 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of DA-8010 in Patients With Overactive Bladder
NCT05282069 ·Status: COMPLETED ·Phase: PHASE3