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Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles

NCT04407065 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2020-05-29

No results posted yet for this study

Summary

The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in patients with history of poor oocytes yield, despite normal response to COH, due to low (\<50%) number of oocytes retrieved per number of follicles \> 14 mm in diameter on day of hCG administration

Conditions

  • Infertility, Female

Interventions

DRUG

Double trigger

Final follicular maturation is triggered by the co-administration of GnRH-agonist (Triptorelin acetate, decapeptyl 0.2 mg, Slough, United Kingdom) and 10000 IU of HCG, 40 and 34 h prior to oocyte retrieval, respectively

DRUG

HCG trigger

Final follicular maturation is triggered by a dose of 10000 IU of HCG 36 h prior to oocyte retrieval

Sponsors & Collaborators

  • Riyadh Fertility and Reproductive Health center

    lead OTHER

Principal Investigators

  • Usama M Fouda, Prof. · Riyadh Fertility and Reproductive Health center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-30
Primary Completion
2020-12-30
Completion
2021-02-02

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04407065 on ClinicalTrials.gov