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Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.

NCT04396977 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2020-05-21

No results posted yet for this study

Summary

To evaluate the inter-arm and inter-period reproducibility of the dermal blood flow response induced by a skin prick of histamine, subjects will receive histamine (10 mg/ml) and negative control skin pricks on the volar surface of both forearms during two subsequent study visits to allow an intra-individual comparison. Changes in dermal blood flow will be measured during the hour after the skin pricks with laser Doppler and/or laser speckle contrast imaging.

Conditions

Interventions

PROCEDURE

Histamine 10 mg/ml skin prick

Skin prick through 5 µL histamine diHCl (10 mg/ml)

PROCEDURE

Placebo (saline) skin prick

Skin prick through 5 µL saline (0.9% NaCl)

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-28
Primary Completion
2019-05-07
Completion
2019-05-07

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04396977 on ClinicalTrials.gov