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Clinical and Immunological Features of the CMV Infection Atypical Course in Immunocompetent Individuals

NCT04392297 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2025-04-06

No results posted yet for this study

Summary

Current study evaluates possible correlations between the content of various cell populations, the genetic material of the virus and antibodies to it in the blood of patients and the risk of thrombosis development in patients with acute CMV infection.

А new method for the early detection of immunological and clinical signs of thromboembolic complications of CMV infection in immunocompetent individuals and the treatment of patients in this category will be developed.

Conditions

  • CMV

Interventions

DIAGNOSTIC_TEST

Bood leukocyte subsets

Determination of blood leukocyte subpopulations: myeloid suppressor cells, T-regulatory cells, T-cells according to the stages of differentiation (naive - effector - memory), activated T-cells; circulating endothelial cells

DIAGNOSTIC_TEST

CMV specific T-cells

CMV specific T-cells detected by flow cytometry

DIAGNOSTIC_TEST

serum CMV IgM / IgG antibodies

serum CMV IgM / IgG antibodies detected by ELISA

Sponsors & Collaborators

  • Belarusian State Medical University

    collaborator OTHER

  • The Republican Research and Practical Center for Epidemiology and Microbiology

    lead OTHER

Principal Investigators

  • Elena Fomina, Dr · Head of the laboratory, RSPCEM

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-07-01
Primary Completion
2025-01-31
Completion
2025-01-31

Countries

  • Belarus

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04392297 on ClinicalTrials.gov