Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells
NCT04382547 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2021-08-23
Summary
Treatment of patients with Covid-19 associated pneumonia using intravenous injection of allogenic pooled olfactory mucosa-derived mesenchymal stem cells
Conditions
Interventions
- BIOLOGICAL
-
Allogenic pooled olfactory mucosa-derived mesenchymal stem cells
Allogenic pooled olfactory mucosa-derived mesenchymal stem cells
- OTHER
-
Standard treatment according to the Clinical protocols
Standard treatment according to the Clinical protocols
Sponsors & Collaborators
-
Belarusian State Medical University
collaborator OTHER -
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
lead OTHER_GOV
Principal Investigators
-
Andrei Y Hancharou, Dr. · Director, the Institute of Biophysics and Cell Engineering of NAS of Belarus
-
Eduard A Dotsenko, Dr., prof. · Head of the chair, Belarusian State Medical University
-
Natalia G Antonevich, Dr. · Head of the Lab of Institute of Biophysics and Cell Engineering of NAS
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-05-11
- Primary Completion
- 2021-06-30
- Completion
- 2021-06-30
Countries
- Belarus
Study Locations
More Related Trials
-
Mesenchymal Stem Cells Therapy in Patients With COVID-19 Pneumonia
NCT04713878 ·Status: COMPLETED ·Phase: NA
-
Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation
NCT04397796 ·Status: TERMINATED ·Phase: PHASE1
-
The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Caused by COVID-19
NCT04798716 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Exosomes in Treating Chronic Cough After COVID-19
NCT05808400 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm C (Fluticasone)
NCT05736874 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Autologous Mesenchymal Stem Cells to Treat Idiopathic Pulmonary Fibrosis
NCT01919827 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia
NCT04527224 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
The Use PUL-042 to Reduce the Infection Rate and Progression to COVID-19 in Adults Exposed to SARS-CoV-2
NCT04313023 ·Status: COMPLETED ·Phase: PHASE2
-
The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection
NCT04312997 ·Status: COMPLETED ·Phase: PHASE2
-
Mesenchymal Stem Cell in Patients With Acute Severe Respiratory Failure
NCT02112500 ·Status: UNKNOWN ·Phase: PHASE2
-
ACT-20 in Patients With Severe COVID-19 Pneumonia
NCT04398303 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Clinical Study of Mesenchymal Progenitor Cell Exosomes Nebulizer for the Treatment of Pulmonary Infection
NCT04544215 ·Status: SUSPENDED ·Phase: PHASE1/PHASE2
-
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
NCT06603246 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety and Potential Efficacy of Human Mesenchymal Stem Cells in Non-Cystic Fibrosis Bronchiectasis
NCT02625246 ·Status: COMPLETED ·Phase: PHASE1
-
Inhaled Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Post-Infectious Cough: A Single-Center Randomized Controlled Clinical Trial
NCT07103980 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis
NCT01385644 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I/IIa Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Idiopathic Pulmonary Fibrosis (IPF)
NCT05468502 ·Status: COMPLETED ·Phase: PHASE1
-
Menstrual Blood-Derived Mesenchymal Stem Cell Injection (SC01009) in the Treatment of Idiopathic Pulmonary Fibrosis
NCT07131150 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)
NCT04494646 ·Status: COMPLETED ·Phase: PHASE2
-
Tocilizumab for Prevention of Respiratory Failure in Patients With Severe COVID-19 Infection
NCT04377659 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Biomarkers of Airway Inflammation (0000-128)
NCT00869596 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)
NCT07048262 ·Status: RECRUITING ·Phase: PHASE2
-
Effects of Bronchial Segmental Endotoxin Instillation in Humans
NCT02392442 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Retrospective Evaluation of Lung Pathology in Subjects With COVID-19
NCT04878913 ·Status: COMPLETED
-
Study of F-652 in Subjects With Corona Virus Disease 2019 (COVID-19) Pneumonia
NCT05205668 ·Status: WITHDRAWN ·Phase: PHASE2