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Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis

NCT04380987 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1366

Last updated 2025-09-09

No results posted yet for this study

Summary

Predi-COVID is a prospective cohort study composed of people positively tested for COVID-19 in Luxembourg, followed digitally for monitoring participants' health evolution and symptoms at home. Participants will be actively followed for 14 days from the time of confirmation of diagnosis, whether they are at the hospital or at home in isolation or quarantine. Short evaluations will be also performed at week 3 and week 4 and then monthly for a period up to 12 months to assess potential long term consequences of COVID-19. A subsample of 200 participants will be contacted to integrate complementary clinical data and collect samples.

The study aims at identifying factors associated with the COVID-19 disease severity. COVID-19 patients with severity criteria will be compared to patients with mild disease managed at home.

A deep phenotyping related to the symptoms of the disease as well as biosampling allowing for laboratory-based and computational analytics will be performed.

Conditions

  • Covid19

Interventions

BIOLOGICAL

Biological sampling

For every symptomatic adult tested positive by RTqPCR, up to 45 mL of blood will be taken, nasopharyngeal and oropharyngeal swab will be performed, an induced sputum and a stool samples will be recovered at the inclusion. As follow-up, 3 weeks after inclusion, up to 45 mL of blood will be taken and a new induced sputum will be recovered.

Sponsors & Collaborators

  • Centre Hospitalier du Luxembourg

    collaborator OTHER

  • Hopitaux Robert Schuman (Luxembourg)

    collaborator UNKNOWN

  • Laboratoire National de Santé (Luxembourg)

    collaborator UNKNOWN

  • University of Luxembourg

    collaborator OTHER

  • Luxembourg Institute of Health

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-04
Primary Completion
2024-09-30
Completion
2024-09-30

Countries

  • Luxembourg

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04380987 on ClinicalTrials.gov