Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures
NCT04368936 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 121
Last updated 2021-10-19
Summary
Febrile seizures (FS) are the most common neurological disorder in chilhood. The etiology of FN is still the subject of numerous studies and it is known that it can depend on genetic predisposition.
Conditions
- Febrile Seizure
Interventions
- GENETIC
-
Isolated DNA, Real Time PCR
We are isolated DNA from the blood sample. To determine the genotypes of the analyzed polymorphisms use real-time PCR using TaqMan essays. When analyzing the KCC2 polymorphisms, the VIC dye gene corresponded to the C allele, and the FAM dye corresponded to the T allele, while at the TRPV1 gene polymorphism, the VIC dye corresponded to the C allele and the FAM dye to the G allele.
Sponsors & Collaborators
-
Institut za Rehabilitaciju Sokobanjska Beograd
lead OTHER
Principal Investigators
-
Sanja Dimitrijevic, PhD · Specila hospital for cerebral palsy and developmental neurology
Eligibility
- Min Age
- 1 Year
- Max Age
- 14 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-03-31
- Primary Completion
- 2019-05-15
- Completion
- 2021-08-31
More Related Trials
-
Tumor Related Epilepsy
NCT02639325 ·Status: RECRUITING
-
Novel Network Analysis of Intracranial Stereoelectroencephalography
NCT03916848 ·Status: UNKNOWN ·Phase: NA
-
Association Between Ferroptosis and Epilepsy
NCT05269901 ·Status: COMPLETED
-
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
NCT06701084 ·Status: RECRUITING ·Phase: NA
-
Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New Drug
NCT00043901 ·Status: COMPLETED ·Phase: PHASE4
-
Phenotyping and Identification of Biological Markers in STXBP1 Encephalopathy
NCT06356233 ·Status: NOT_YET_RECRUITING
-
Evaluating the Role of Inflammation in Neonatal Epileptogenesis
NCT04259125 ·Status: COMPLETED
-
Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age
NCT06278428 ·Status: RECRUITING
-
Neonatal Seizures: Semiology, Etiology, Therapy and Prognosis Correlations
NCT06308185 ·Status: ACTIVE_NOT_RECRUITING
-
The Mosaic Brain: a New Diagnostic Approach in Focal Epilepsies
NCT06602570 ·Status: NOT_YET_RECRUITING
-
Cognitive AED Outcomes in Pediatric Localization Related Epilepsy (COPE)
NCT01891890 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures
NCT00275912 ·Status: COMPLETED ·Phase: PHASE4
-
Open-label, Pharmacokinetic, Safety and Efficacy Study of Adjunctive Brivaracetam in Children With Epilepsy.
NCT00422422 ·Status: COMPLETED ·Phase: PHASE2
-
Value of Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
NCT05215366 ·Status: UNKNOWN
-
Prevalence and Pattern of Headache in Pediatric Epilepsy
NCT06868251 ·Status: NOT_YET_RECRUITING
-
Sensory Perception in Children With Epilepsy
NCT06818357 ·Status: NOT_YET_RECRUITING
-
Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalopathies
NCT02239276 ·Status: NO_LONGER_AVAILABLE
-
Association of Brain Derived Neurotrophic Factor (BDNF) rs6265 Gene Polymorphism With Susceptibility to Epilepsy
NCT05096871 ·Status: UNKNOWN
-
Epigenetics and Gut Microbiota in Children With Epilepsy
NCT04063007 ·Status: UNKNOWN ·Phase: NA
-
Nucleotide Protein -3 in Epileptic Children
NCT04219930 ·Status: UNKNOWN
-
Pharmacokinetics of Anti-epileptic Drugs in Obese Children
NCT02993861 ·Status: COMPLETED
-
Psychiatric Comorbidities in Children With Generalized Epilepsy
NCT06194422 ·Status: NOT_YET_RECRUITING
-
A Study of GWP42006 in People With Focal Seizures - Part B
NCT02365610 ·Status: COMPLETED ·Phase: PHASE2
-
Cognitive Impact of Benzodiazepin Withdrawn After Curative Epilepsy Surgery in Children With Focal Epilepsy
NCT03803046 ·Status: TERMINATED
-
Population Pharmacokinetics of Antiepileptic in Pediatrics
NCT03196466 ·Status: COMPLETED