Atovaquone and Azithromycin Combination for Confirmed COVID-19 Infection
NCT04339426 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2022-03-04
Summary
This study will evaluate anti-malarial/anti-infective single-agent and in combination for patients with confirmed COVID-19 infection. The first combination to be evaluated is atovaquone and azithromycin.
Conditions
- Covid19
Interventions
- DRUG
-
Atovaquone/Azithromycin
Atovaquone 750 mg PO Q12H for up to 10 Days Azithromycin 500 mg PO Daily 1 followed by 250 mg PO Daily for up to 10 days (days 2-10)
Sponsors & Collaborators
-
HonorHealth Research Institute
lead OTHER
Principal Investigators
-
Michael Gordon, MD · HonorHealth Research Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 95 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-20
- Primary Completion
- 2022-02-11
- Completion
- 2022-02-11
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease
NCT07213765 ·Status: RECRUITING ·Phase: PHASE4
-
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
NCT04677543 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of an Intensive 3-round MDA Strategy Towards Yaws Eradication
NCT03490123 ·Status: COMPLETED ·Phase: PHASE4
-
Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care Workers
NCT04681001 ·Status: COMPLETED ·Phase: NA
-
Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease
NCT00004689 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed Covid-19 Infection
NCT04523831 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy
NCT00002085 ·Status: COMPLETED ·Phase: NA
-
Study of "Sputnik Lite" for the Prevention of COVID-19 With Altered Antigenic Composition.
NCT06057025 ·Status: UNKNOWN ·Phase: PHASE3
-
Hypertonic Saline for MAC
NCT04921943 ·Status: RECRUITING ·Phase: PHASE4
-
The COVID-19 Back-to-Normal Study: Analysis of Multiple Outcomes
NCT04832932 ·Status: ACTIVE_NOT_RECRUITING
-
Study to Assess the Efficacy and Safety of STI-1558 in Adult Subjects With Mild or Moderate (COVID-19)
NCT05716425 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate a Single Dose of LTX-109 in Subjects With COVID-19 (Coronavirus Disease 2019) Infection.
NCT04854928 ·Status: UNKNOWN ·Phase: PHASE2
-
Azithromycin for Meningococcal Carriage
NCT06618534 ·Status: RECRUITING ·Phase: PHASE2
-
Azithromycin Reduction to Reach Elimination of Trachoma B
NCT06289647 ·Status: WITHDRAWN ·Phase: PHASE4
-
Antimicrobial Resistance During the SARS-CoV-2 (COVID-19) Pandemic
NCT06334731 ·Status: COMPLETED
-
MRSA Decolonization in Complicated Carriage
NCT05268120 ·Status: RECRUITING ·Phase: NA
-
To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.
NCT00910871 ·Status: COMPLETED ·Phase: PHASE2
-
the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
NCT05291468 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult Volunteers
NCT05942820 ·Status: TERMINATED ·Phase: PHASE1
-
Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
NCT04677569 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19
NCT04551755 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of Azithromycin Plus Doxycycline Versus Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever
NCT05398055 ·Status: RECRUITING ·Phase: PHASE3
-
TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis
NCT00523926 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Trial of Inhaled Molgramostim in Non-tuberculous Mycobacterial (NTM) Infection
NCT03421743 ·Status: COMPLETED ·Phase: PHASE2
-
Pityriasis Lichenoides Chronica, Role of Streptococcal Infection and Azithromycin
NCT03831269 ·Status: UNKNOWN ·Phase: NA