ATG-008 Combined With Toripalimab in Advanced Solid Tumors
NCT04337463 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2021-05-17
Summary
This is an open-label, single-arm study with dose-escalation and expansion phases to access ATG-008 combined with Toripalimab in patients with advanced solid tumors.
Conditions
- Advanced Solid Tumor
Interventions
- DRUG
-
ATG-008
Tablet
- DRUG
-
Toripalimab
IV infusion
Sponsors & Collaborators
-
Sichuan University
lead OTHER
Principal Investigators
-
Li Zheng · West China Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-23
- Primary Completion
- 2022-05-01
- Completion
- 2022-12-01
Countries
- China
Study Locations
More Related Trials
-
Toripalimab Combined With Chemoradiotherapy in Patients With Locoregionally-advanced Nasopharyngeal Carcinoma
NCT04446663 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase I Study of WJ47156 Monotherarpy and in Combination With Other Therapy in Advanced Solid Tumors
NCT06571422 ·Status: RECRUITING ·Phase: PHASE1
-
APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors
NCT04785196 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Toripalimab Plus Etoposide and Platinum-based Chemotherapy for Genitourinary Small Cell Carcinoma
NCT05760053 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Toripalimab for Limited-Stage Small Cell Lung Cancer Following Concurrent Chemoradiotherapy
NCT04418648 ·Status: TERMINATED ·Phase: PHASE2
-
Toripalimab(JS001) as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors
NCT03810339 ·Status: RECRUITING ·Phase: PHASE2
-
Toripalimab Combined With Radiotherapy in the Treatment of Oligometastatic Nasopharyngeal Carcinoma
NCT05147844 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase Ib/II Clinical Study of LBL-007 in Combination With Toripalimab in Treatment of Advanced Malignant Tumors
NCT05102006 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
RT-01 Monotherapy and in Combination With Nivolumab in Patients With Advanced Solid Tumors
NCT05122572 ·Status: UNKNOWN ·Phase: PHASE1
-
Efficacy and Safety of Toripalimab (JS001) Combined With Pemetrexed and Anlotinib for Patients With T790M Positive Non-Small Cell Lung Cancer After Osimertinib Resistance
NCT04316351 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors
NCT07038005 ·Status: RECRUITING ·Phase: PHASE1
-
Toripalimab in Combination With Platinum-based Chemotherapy for Mutation-negative Stage IV Oligometastatic NSCLC
NCT05055583 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 in Advanced Solid Tumors
NCT06088004 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase I/II Study of TJ004309 for Advanced Solid Tumor
NCT04322006 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma
NCT04376866 ·Status: RECRUITING ·Phase: PHASE3
-
SMET12 and Toripalimab Combined Chemotherapy in Patients With EGFR Positive Advanced Non-small Cell Lung Cancer (NSCLC)
NCT06208033 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC
NCT06127303 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of WX390 Combined With Toripalimab in Patients With Advanced Solid Tumors
NCT06117566 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
The Optimal Radioimmunotherapy Combinations for Advanced TNBC
NCT06735131 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
NCT05955105 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Assess LBL-007 in Combination With Toripalimab and Axitinib Tablets Subjects With Advanced Melanoma
NCT04640545 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetics and Efficacy of SCT-I10A in Patients With Advanced Solid Tumors or Lymphoma
NCT03821363 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of Recombinant Human Anti-PD-1 Monoclonal Antibody in Patients With Advanced Tumours
NCT03852823 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
NCT04636762 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Safety and Tolerability of JCXH-212 Monotherapy and Combined With Toripalimab in the Treatment of Malignant Solid Tumors
NCT05579275 ·Status: RECRUITING ·Phase: EARLY_PHASE1