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CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION

NCT04333732 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 3411

Last updated 2024-03-26

Study results available
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Summary

The objective of CROWN CORONATION is the prevention of symptomatic COVID-19 by using combinations of approved and safe repurposed interventions, with complementary mechanisms of action.

Conditions

  • COVID 19

Interventions

DRUG

MR or M-M-R II ® vaccine

Education and surveillance plus MR or M-M-R II ® vaccine

DRUG

Placebo

Placebo injection

Sponsors & Collaborators

  • COVID -19 Therapeutics Accelerator

    collaborator UNKNOWN

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Michael S. Avidan, MBBCh · Washington Univeristy School of Medicine

  • Ramani Moonesinghe, MD · University College, London

  • Helen Rees, MD · Wits University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-04
Primary Completion
2021-08-10
Completion
2021-12-03
FDA Drug
Yes

Countries

  • United States
  • Ghana
  • South Africa
  • United Kingdom
  • Zambia

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04333732 on ClinicalTrials.gov