COVID-19 in Patients With Pre-existing Cirrhosis (COVID-Cirrhosis-CHESS2002): A Multicentre Observational Study

Summary

COVID-19 pandemic with SARS-CoV-2 infection has become a global challenge. Though most cases of COVID-19 are mild, the disease can also be fatal. Patients with liver cirrhosis are more susceptible to damage from SARS-CoV-2 infection considering their immunocompromised status. The spectrum of disease and factors that influence the disease course in COVID-19 cases with liver cirrhosis are incompletely defined. This muilticentre observational study (COVID-Cirrhosis-CHESS2002) aims to study the clinical characteristics and risk factors associated with specific outcomes in COVID-19 patients with pre-existing liver cirrhosis.

Conditions

• COVID-19
• Liver Cirrhosis

Sponsors & Collaborators

• Renmin Hospital of Wuhan University

  collaborator OTHER

• LanZhou University

  collaborator OTHER

• Minda Hospital Affiliated to Hubei University for Nationalities

  collaborator UNKNOWN

• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

  collaborator OTHER

• The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture

  collaborator OTHER

• Tianjin Second People's Hospital

  collaborator OTHER

• The Sixth People's Hospital of Shenyang

  collaborator OTHER

• Guangxi Zhuang Autonomous Region

  collaborator UNKNOWN

• Shenzhen Third People's Hospital

  collaborator OTHER

• Ankang Central Hospital

  collaborator OTHER

• Xingtai People's Hospital

  collaborator OTHER

• Dalian Sixth People's Hospital

  collaborator UNKNOWN

• The Central Hospital of Lishui City

  collaborator OTHER

• The Affiliated Third Hospital of Jiangsu University

  collaborator UNKNOWN

• Suizhou Hospital, Hubei University of Medicine

  collaborator UNKNOWN

• Hepatopancreatobiliary Surgery Institute of Gansu Province

  lead OTHER

Principal Investigators

• Mingkai Chen, MD · Renmin Hospital of Wuhan University

• Xiaolong Qi, MD · LanZhou University

• Fengmei Wang, MD · Tianjin Second People's Hospital

• Ye Gu, MD · The Sixth People's Hospital of Shenyang

• Zicheng Jiang, MD · Ankang Central Hospital

• Guo Zhang, MD · Guangxi Zhuang Autonomous Region

• Yong Zhang, MD · Dalian Sixth People's Hospital

• Dengxiang Liu, MD · Xingtai People's Hospital

• Qing He, MD · Shenzhen Third People's Hospital

• Hua Yang, MD · Minda Hospital Affiliated to Hubei University for Nationalities

• Zhengyan Wang, MD · Suizhou Hospital, Hubei University of Medicine

• Bin Xiong, MD · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

• Xiaodan Li, MD · The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture

• Hongguang Zhang, MD · The Affiliated Third Hospital of Jiangsu University

• Chuxiao Shao, MD · The Central Hospital of Lishui City

• Hongmei Yue, MD · LanZhou University

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-03-30

Primary Completion

2021-02-10

Completion

2021-02-10

Countries

• China

Study Locations