Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation
NCT04322890 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 6000
Last updated 2024-10-22
Summary
The purpose of this study is to assess the Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.
Conditions
- Non Small Cell Lung Cancer
- EGFR Gene Mutation
- ALK Gene Mutation
- ROS1 Gene Mutation
- MET Gene Mutation
Interventions
- DRUG
-
Osimertinib 80mg, po, qd;
- DRUG
-
Alectinib 150 MG
Alectinib 600mg, po, qd; Lorlatinib, 100mg, po, qd;
- DRUG
-
Crizotinib 250 MG
Crizotinib 250 MG po bid.
- DRUG
-
Savolitinib, Crizotinib.
Savolitinib, 300mg po qd.
- DRUG
-
500mg, ivgtt, every 21day.
Sponsors & Collaborators
-
Hunan Province Tumor Hospital
lead OTHER
Principal Investigators
-
Yongchang Zhang, MD · Hunan Cancer Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-16
- Primary Completion
- 2026-12-24
- Completion
- 2027-12-24
Countries
- China
Study Locations
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