The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective?
NCT04322786 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1302508
Last updated 2020-11-13
Summary
The study use UK based linked electronic health records from the Clinical Research Datalink (CALIBER) of 5.6 million individuals to conduct a matched case-control study to investigate the incidence of influenza in individuals prescribed ACEI compared to those not prescribed ACEI.
Conditions
- Covid-19, Coronavirus, Angiotensin Converting Enzyme Inhibitors, Influenza, Electronic Health Records, Epidemiology, Comorbidity, Incidence, United Kingdom
Interventions
- DRUG
-
ACE inhibitor
Any prescription of ACE inhibitor
Sponsors & Collaborators
-
University College, London
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-01-01
- Primary Completion
- 2016-05-31
- Completion
- 2021-03-31
More Related Trials
-
Antiviral Therapy for Influenza A H1N1
NCT00985582 ·Status: COMPLETED
-
Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia
NCT03900988 ·Status: RECRUITING ·Phase: PHASE3
-
Efficacy and Safety of Molnupiravir in Healthy Participants Inoculated With Experimental Influenza Virus (MK-4482-019)
NCT05818124 ·Status: COMPLETED ·Phase: PHASE1
-
Safety And Pharmacokinetics Study Of PF-04287881 In Healthy Adults
NCT00793000 ·Status: COMPLETED ·Phase: PHASE1
-
ADC189 Tablets on Influenza A Virus Infection/Influenza B Virus Infection
NCT06342921 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Evaluating The Safety And Clinical Efficacy Of Elderberry Extract In Patients With Influenza
NCT03410862 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Safety, Tolerability and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
NCT05030324 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation the Safety and Tolerance of GP681 Tablets in Healthy Subjects
NCT04729764 ·Status: COMPLETED ·Phase: PHASE1
-
Norketotifen for the Treatment of Uncomplicated Influenza-like Illness
NCT04043923 ·Status: COMPLETED ·Phase: PHASE2
-
Baloxavir Versus Oseltamivir for Nursing Home Influenza Outbreaks
NCT05012189 ·Status: UNKNOWN ·Phase: PHASE4
-
Alleviation of Common Cold Symptoms
NCT06106880 ·Status: COMPLETED ·Phase: PHASE1
-
A Study on Higher-dose Oseltamivir Treatment's Impact on Viral Clearance and Clinical Recovery in Adults Hospitalized With Influenza
NCT01052961 ·Status: COMPLETED ·Phase: PHASE4
-
A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts
NCT06094010 ·Status: RECRUITING ·Phase: PHASE3
-
Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults
NCT03154515 ·Status: COMPLETED ·Phase: PHASE4
-
To Compare the Safety and PK/ PD Characteristics of ADC189 Between Hepatic Impairment and Normal Hepatic Function Subjects
NCT06485401 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Efficacy and Safety of XC221 in the Treatment of Influenza and Other Acute Respiratory Viral Infections
NCT03455491 ·Status: COMPLETED ·Phase: PHASE2
-
Suraxavir Marboxil And Oseltamivir for Influenza Prophylaxis Under a Hospital-based Setting
NCT07236814 ·Status: RECRUITING ·Phase: PHASE3
-
A Clinical Trial of KT07 Capsule in the U.S.A
NCT02867358 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness
NCT05689034 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (SARS-CoV-2 Infected)
NCT04668235 ·Status: COMPLETED ·Phase: PHASE3
-
Dose Range Study to Evaluate the Efficacy and Safety of AV5080 in Patients With Influenza
NCT05095545 ·Status: COMPLETED ·Phase: PHASE2
-
Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients
NCT04570501 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection
NCT02532283 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza
NCT03684044 ·Status: COMPLETED ·Phase: PHASE3
-
Oseltamivir and Baloxavir Marboxil for Prophylaxis Against Influenza Under a Hospital-based Setting
NCT06762587 ·Status: NOT_YET_RECRUITING ·Phase: NA