Phase Ib First in Human Dose Escalation of GT103 in Refractory, Advanced Stage Non-Small Cell Lung Cancer (TOP 1902)
NCT04314089 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 31
Last updated 2025-06-17
Summary
The purpose of this research study is to determine the maximum tolerated dose of GT103 and investigate the safety and effectiveness of the study drug.
Conditions
Interventions
- DRUG
-
GT103
intravenously (dose depending)
Sponsors & Collaborators
-
Edward Patz
lead OTHER
Principal Investigators
-
Jeffrey Clarke, MD · Duke University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-09
- Primary Completion
- 2024-04-11
- Completion
- 2024-12-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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