Duloxetine for PHN

Summary

In this study, the investigators aim to investigate the preventive efficacy of prophylactic oral duloxetine during acute herpes zoster on postherpetic neuralgia and its safety.

Conditions

• Postherpetic Neuralgia

Interventions

DRUG

Duloxetine

Oral Duloxetine (up to 60 mg per day) will be given, titrated, tapered in accordance with the pain intensity during the acute herpes zoster period.

Sponsors & Collaborators

• China-Japan Friendship Hospital

  collaborator OTHER

• Tianjin Medical University Second Hospital

  collaborator OTHER

• Taiyuan Central Hospital of Shanxi Medical University

  collaborator OTHER

• Linfen Fourth People's Hospital

  collaborator UNKNOWN

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Qingdao Municipal Hospital (Group)

  collaborator UNKNOWN

• The Second People's Hospital of Huai'an

  collaborator OTHER

• First Hospital of China Medical University

  collaborator OTHER

• Second Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• Fujian Provincial Hospital

  collaborator OTHER

• Cangzhou Central Hospital

  collaborator OTHER

• The People's Hospital of Fujian Province

  collaborator UNKNOWN

• Beijing Tsinghua Chang Gung Hospital

  collaborator OTHER

• Peking University International Hospital

  collaborator OTHER

• Tianjin First Central Hospital

  collaborator OTHER

• Tianjin Huanhu Hospital

  collaborator OTHER

• Baoding First Central Hospital

  collaborator OTHER

• Beijing Tiantan Hospital

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

50 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-03-01

Primary Completion

2023-05-16

Completion

2023-05-16

Countries

• China

Study Locations