The Effect of Exenatide on Fasting Bile Acids
NCT04303819 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38
Last updated 2020-06-11
Summary
Newly diagnosed T2DM participants without hypoglycemic drugs intake were retrospective analyzed. Plasma total bile acids in fasting state (FTBAs) and other parameters were compared before and after exenatide treatment and correlation analysis between changes of FTBAs and glycemic parameters.
Conditions
- Type 2 Diabetes Mellitus in Obese
Interventions
- DRUG
-
Exenatide treatment
12 weeks of exenatide injection, 5 μg twice a day by subcutaneous injection for 4 weeks, followed by 10 μg twice a day for 8 weeks, as recommended by the drug manufacturer.
Sponsors & Collaborators
-
Beijing Chao Yang Hospital
lead OTHER
Principal Investigators
-
Boyu Li, PHD · Beijing Chao Yang Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-05
- Primary Completion
- 2020-01-28
- Completion
- 2020-01-31
- FDA Drug
- Yes
Countries
- China
Study Locations
More Related Trials
-
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin
NCT00099320 ·Status: COMPLETED ·Phase: PHASE3
-
The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
NCT01342042 ·Status: UNKNOWN ·Phase: PHASE2
-
Specific Clinical Experience Investigation for Long-term Use of Exenatide (Byetta Subcutaneous Injection)
NCT01817569 ·Status: COMPLETED
-
The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
NCT03239119 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell Function
NCT00845182 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Exenatide on Abdominal Fat Distribution in Patients With Type 2 Diabetes Pretreated With Metformin
NCT00701935 ·Status: TERMINATED ·Phase: PHASE2
-
Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus.
NCT03007329 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients
NCT01147627 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Who Are Treated With Oral Antidiabetic(s)
NCT00577824 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Safety and Pharmacokinetics/Pharmacodynamics of Sustained Release(SR) Exenatide
NCT00964262 ·Status: COMPLETED ·Phase: PHASE1
-
Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 Diabetes
NCT03196362 ·Status: UNKNOWN ·Phase: PHASE4
-
A Single-Center, Open-Label, Single Ascending Dose Study of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes Mellitus
NCT07347080 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes
NCT05353686 ·Status: COMPLETED ·Phase: PHASE2
-
Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β Cell
NCT03180281 ·Status: UNKNOWN ·Phase: NA
-
Safety and Tolerability of Lixisenatide in Combination With Oral Anti-Diabetic Treatment in Patients With Type 2 Diabetes
NCT01940965 ·Status: COMPLETED ·Phase: PHASE3
-
A Single-Dose Study of MK6349 in Patients With Type 2 Diabetes (6349-002)
NCT00943371 ·Status: TERMINATED ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 44847 in Female and Male Patients With Type 2 Diabetes
NCT02211963 ·Status: COMPLETED ·Phase: PHASE1
-
Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy
NCT03030300 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus
NCT04889157 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Pharmacokinetic Comparison of Two Recombinant Exendin-4 Formulations in Chinese Healthy Male Subjects
NCT03199261 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease
NCT03796975 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Effect on Glucose Control and Safety and Tolerability of LY2148568 In Japanese Patients With Type 2 Diabetes
NCT00382239 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 14332 CL as Tablet in Female and Male Patients With Type 2 Diabetes
NCT02212925 ·Status: TERMINATED ·Phase: PHASE1
-
A Trial To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Single Doses Of PF-04937319 In Subjects With Type 2 Diabetes Mellitus
NCT01044537 ·Status: COMPLETED ·Phase: PHASE1
-
A Double-Blind, Randomized, Parallel, Comparative Study to Evaluate the Efficacy and Safety of an Antidiabetic Agent Repaglinide for the Treatment of Type 2 Diabetes Mellitus Patients
NCT00336310 ·Status: UNKNOWN ·Phase: PHASE4